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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CANT1
All Species:
41.82
Human Site:
Y225
Identified Species:
76.67
UniProt:
Q8WVQ1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVQ1
NP_001153244.1
401
44840
Y225
A
V
K
D
E
R
L
Y
V
G
G
L
G
K
E
Chimpanzee
Pan troglodytes
XP_523734
401
44895
Y225
A
V
K
D
E
R
L
Y
V
G
G
L
G
K
E
Rhesus Macaque
Macaca mulatta
XP_001109105
401
44859
Y225
A
V
K
E
E
H
L
Y
V
G
G
L
G
K
E
Dog
Lupus familis
XP_848726
401
44706
Y225
A
V
K
D
E
H
L
Y
V
G
G
L
G
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCF1
403
45634
Y227
A
V
K
D
E
H
L
Y
V
G
G
L
G
K
E
Rat
Rattus norvegicus
Q8K4Y7
403
45640
Y227
A
V
K
D
E
H
L
Y
V
G
G
L
G
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517798
396
43895
Y220
A
V
K
D
E
H
L
Y
V
G
G
L
G
K
E
Chicken
Gallus gallus
NP_001026752
311
34198
D137
L
V
L
S
A
S
G
D
S
V
T
V
E
W
D
Frog
Xenopus laevis
NP_001079373
400
44682
Y224
A
V
K
D
E
Q
L
Y
V
G
G
L
G
K
E
Zebra Danio
Brachydanio rerio
NP_999908
404
45329
Y228
A
V
K
D
E
H
L
Y
V
G
G
L
G
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650074
419
47660
Y239
T
V
K
E
Q
T
L
Y
V
G
S
M
G
K
E
Honey Bee
Apis mellifera
XP_623385
394
45357
Y218
T
V
K
D
E
H
L
Y
V
G
S
M
G
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792609
398
44256
F222
A
V
K
D
Q
H
L
F
V
G
G
L
G
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.2
88.7
N.A.
87.3
86.5
N.A.
74.8
56.3
74.3
68.3
N.A.
45.8
45.8
N.A.
47.8
Protein Similarity:
100
99.2
97.7
93.2
N.A.
93.5
92.8
N.A.
85.2
62.3
84.5
79.4
N.A.
58.7
64
N.A.
67.8
P-Site Identity:
100
100
86.6
93.3
N.A.
93.3
93.3
N.A.
93.3
6.6
93.3
93.3
N.A.
60
73.3
N.A.
80
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
20
100
93.3
N.A.
80
80
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
77
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
77
0
0
0
8
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
16
77
0
0
0
0
0
0
0
8
0
93
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
93
77
0
93
0
0
% G
% His:
0
0
0
0
0
62
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
93
0
0
0
0
0
0
0
0
0
0
93
0
% K
% Leu:
8
0
8
0
0
0
93
0
0
0
0
77
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
16
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
8
0
0
8
0
16
0
0
0
0
% S
% Thr:
16
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% T
% Val:
0
100
0
0
0
0
0
0
93
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _