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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR60
All Species:
4.55
Human Site:
S197
Identified Species:
11.11
UniProt:
Q8WVS4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVS4
NP_060521.4
1066
122645
S197
R
K
L
Q
Y
G
D
S
K
D
N
P
L
K
Y
Chimpanzee
Pan troglodytes
XP_001151045
1066
122736
S197
R
K
L
R
Y
G
D
S
K
D
N
P
L
K
Y
Rhesus Macaque
Macaca mulatta
XP_001093764
713
80020
Dog
Lupus familis
XP_539942
1085
123525
P199
H
K
D
R
H
W
E
P
D
A
D
K
S
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C761
999
115364
R172
S
K
I
R
T
E
E
R
E
R
R
D
E
D
S
Rat
Rattus norvegicus
XP_001061189
1003
115646
A168
V
E
K
K
V
H
I
A
S
K
L
R
M
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511820
1056
122263
G197
R
K
L
Q
F
I
D
G
K
D
N
H
V
K
Y
Chicken
Gallus gallus
XP_418555
834
94772
E69
H
K
S
K
R
S
V
E
E
Y
S
C
E
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662902
1034
120019
E181
E
S
D
R
Y
R
L
E
Y
D
E
K
Q
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785240
1073
123047
E222
K
D
R
E
R
R
K
E
K
E
S
N
D
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
64.5
57.7
N.A.
70.7
70.8
N.A.
57.4
46.7
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
99.3
65.6
69.1
N.A.
82.7
82.5
N.A.
74.1
59.6
N.A.
57.9
N.A.
N.A.
N.A.
N.A.
50.6
P-Site Identity:
100
93.3
0
6.6
N.A.
6.6
0
N.A.
66.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
0
33.3
N.A.
33.3
33.3
N.A.
80
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
10
20
0
0
0
30
0
10
40
10
10
10
20
10
% D
% Glu:
10
10
0
10
0
10
20
30
20
10
10
0
20
10
20
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
20
0
10
0
0
0
0
0
0
10
% G
% His:
20
0
0
0
10
10
0
0
0
0
0
10
0
10
0
% H
% Ile:
0
0
10
0
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
60
10
20
0
0
10
0
40
10
0
20
0
30
0
% K
% Leu:
0
0
30
0
0
0
10
0
0
0
10
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
30
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
20
0
0
0
% P
% Gln:
0
0
0
20
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
30
0
10
40
20
20
0
10
0
10
10
10
0
10
10
% R
% Ser:
10
10
10
0
0
10
0
20
10
0
20
0
10
10
10
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
10
0
10
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
30
0
0
0
10
10
0
0
0
0
30
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _