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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR60
All Species:
10.61
Human Site:
S304
Identified Species:
25.93
UniProt:
Q8WVS4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVS4
NP_060521.4
1066
122645
S304
H
R
N
R
G
A
S
S
K
R
D
G
T
S
S
Chimpanzee
Pan troglodytes
XP_001151045
1066
122736
S304
H
R
N
R
G
A
S
S
K
R
D
G
T
S
S
Rhesus Macaque
Macaca mulatta
XP_001093764
713
80020
D30
D
D
F
E
D
Y
E
D
D
F
E
V
C
D
G
Dog
Lupus familis
XP_539942
1085
123525
E330
K
R
D
K
Y
A
K
E
K
S
N
S
S
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8C761
999
115364
D258
L
S
D
R
E
V
E
D
R
H
R
E
K
R
H
Rat
Rattus norvegicus
XP_001061189
1003
115646
E250
K
K
D
R
H
S
K
E
K
G
S
S
L
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511820
1056
122263
S306
H
R
N
Q
G
A
S
S
K
R
E
S
G
L
H
Chicken
Gallus gallus
XP_418555
834
94772
P151
T
H
I
Y
N
S
D
P
E
P
D
N
F
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662902
1034
120019
S275
E
R
K
H
K
E
A
S
D
S
K
R
S
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785240
1073
123047
Y312
E
S
N
Q
D
D
G
Y
E
D
D
F
E
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
64.5
57.7
N.A.
70.7
70.8
N.A.
57.4
46.7
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
99.3
65.6
69.1
N.A.
82.7
82.5
N.A.
74.1
59.6
N.A.
57.9
N.A.
N.A.
N.A.
N.A.
50.6
P-Site Identity:
100
100
0
26.6
N.A.
6.6
20
N.A.
60
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
6.6
53.3
N.A.
20
40
N.A.
73.3
33.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
40
10
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
10
30
0
20
10
10
20
20
10
40
0
0
20
20
% D
% Glu:
20
0
0
10
10
10
20
20
20
0
20
10
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
10
0
10
10
0
0
% F
% Gly:
0
0
0
0
30
0
10
0
0
10
0
20
10
0
20
% G
% His:
30
10
0
10
10
0
0
0
0
10
0
0
0
0
20
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
10
10
10
10
0
20
0
50
0
10
0
10
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
40
0
10
0
0
0
0
0
10
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
50
0
40
0
0
0
0
10
30
10
10
0
10
10
% R
% Ser:
0
20
0
0
0
20
30
40
0
20
10
30
20
60
20
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
10
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _