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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR60
All Species:
17.88
Human Site:
S474
Identified Species:
43.7
UniProt:
Q8WVS4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVS4
NP_060521.4
1066
122645
S474
F
V
D
F
A
S
A
S
H
R
Q
K
S
R
T
Chimpanzee
Pan troglodytes
XP_001151045
1066
122736
S474
F
V
D
F
A
S
A
S
H
R
Q
K
S
R
T
Rhesus Macaque
Macaca mulatta
XP_001093764
713
80020
Q181
N
T
K
Q
A
Y
V
Q
C
N
E
D
N
V
E
Dog
Lupus familis
XP_539942
1085
123525
S501
F
V
D
F
A
T
A
S
R
R
Q
K
S
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8C761
999
115364
S417
F
V
D
F
A
T
A
S
H
R
Q
K
S
R
S
Rat
Rattus norvegicus
XP_001061189
1003
115646
S421
F
V
D
F
A
T
A
S
H
R
Q
K
S
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511820
1056
122263
K471
L
M
D
F
V
T
A
K
E
R
Q
V
S
R
N
Chicken
Gallus gallus
XP_418555
834
94772
G302
D
M
Y
I
R
N
Y
G
K
M
N
T
K
Q
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662902
1034
120019
K445
I
I
D
F
V
S
A
K
Q
R
E
I
S
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785240
1073
123047
A489
T
F
I
N
F
V
A
A
K
Q
R
Q
I
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
64.5
57.7
N.A.
70.7
70.8
N.A.
57.4
46.7
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
99.3
65.6
69.1
N.A.
82.7
82.5
N.A.
74.1
59.6
N.A.
57.9
N.A.
N.A.
N.A.
N.A.
50.6
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
86.6
N.A.
46.6
0
N.A.
40
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
93.3
N.A.
100
100
N.A.
60
20
N.A.
60
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
60
0
80
10
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
10
0
70
0
0
0
0
0
0
0
0
10
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
20
0
0
0
10
% E
% Phe:
50
10
0
70
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% H
% Ile:
10
10
10
10
0
0
0
0
0
0
0
10
10
0
0
% I
% Lys:
0
0
10
0
0
0
0
20
20
0
0
50
10
0
10
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
20
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
10
0
0
0
10
10
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
10
10
10
60
10
0
20
0
% Q
% Arg:
0
0
0
0
10
0
0
0
10
70
10
0
0
60
0
% R
% Ser:
0
0
0
0
0
30
0
50
0
0
0
0
70
10
20
% S
% Thr:
10
10
0
0
0
40
0
0
0
0
0
10
0
0
30
% T
% Val:
0
50
0
0
20
10
10
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _