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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF133
All Species:
17.58
Human Site:
S54
Identified Species:
38.67
UniProt:
Q8WVZ7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVZ7
NP_631914.1
376
42294
S54
H
V
G
N
H
V
L
S
E
L
G
E
T
G
V
Chimpanzee
Pan troglodytes
XP_001146813
376
42211
S54
H
V
G
N
H
V
L
S
E
L
G
E
T
G
V
Rhesus Macaque
Macaca mulatta
XP_001084535
376
42220
S54
H
V
G
N
H
V
L
S
E
L
G
E
T
G
V
Dog
Lupus familis
XP_549171
512
55498
W144
T
G
V
N
R
T
V
W
E
L
S
E
E
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q14B02
382
43083
S54
H
V
G
N
R
M
L
S
E
L
G
E
T
G
V
Rat
Rattus norvegicus
Q6AY01
381
42853
S54
H
V
G
N
R
M
L
S
E
L
G
E
T
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513019
558
60556
W175
P
G
G
N
R
T
V
W
E
L
G
E
D
G
V
Chicken
Gallus gallus
Q90972
381
42801
R54
T
F
D
D
L
P
A
R
F
G
Y
R
L
P
A
Frog
Xenopus laevis
Q8AWW4
404
44844
G57
Y
G
E
E
G
E
I
G
V
F
G
Q
D
S
P
Zebra Danio
Brachydanio rerio
Q566M8
419
46332
A54
T
Y
V
D
P
D
T
A
E
V
R
T
E
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q06003
461
52604
C84
V
E
H
G
N
M
L
C
N
M
E
F
A
Q
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96
38.8
N.A.
72.7
71.6
N.A.
34
23.3
45
30.5
N.A.
24.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
96.8
52.9
N.A.
82.4
82.4
N.A.
47.4
41.7
60.6
51.5
N.A.
43.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
40
N.A.
86.6
86.6
N.A.
53.3
0
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
46.6
N.A.
93.3
93.3
N.A.
60
6.6
26.6
26.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
19
0
10
0
0
0
0
0
0
19
0
0
% D
% Glu:
0
10
10
10
0
10
0
0
73
0
10
64
19
0
10
% E
% Phe:
0
10
0
0
0
0
0
0
10
10
0
10
0
0
0
% F
% Gly:
0
28
55
10
10
0
0
10
0
10
64
0
0
64
0
% G
% His:
46
0
10
0
28
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
10
0
55
0
0
64
0
0
10
0
0
% L
% Met:
0
0
0
0
0
28
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
64
10
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
10
10
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
0
37
0
0
10
0
0
10
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
46
0
0
10
0
0
10
0
% S
% Thr:
28
0
0
0
0
19
10
0
0
0
0
10
46
0
10
% T
% Val:
10
46
19
0
0
28
19
0
10
10
0
0
0
0
64
% V
% Trp:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _