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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APH1B All Species: 0
Human Site: S103 Identified Species: 0
UniProt: Q8WW43 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WW43 NP_112591.2 257 28460 S103 K A S E G L K S I N P G E T A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105067 257 28566
Dog Lupus familis XP_544714 346 38112
Cat Felis silvestris
Mouse Mus musculus Q8C7N7 257 28685
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514807 225 24964
Chicken Gallus gallus XP_001233302 256 28091
Frog Xenopus laevis NP_001089056 247 26905
Zebra Danio Brachydanio rerio Q8JHE9 258 28628
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQG2 238 26419
Honey Bee Apis mellifera XP_392345 240 26608
Nematode Worm Caenorhab. elegans O45876 308 33529
Sea Urchin Strong. purpuratus XP_783542 260 29305
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L9G7 250 27517
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.7 58 N.A. 84 N.A. N.A. 58.7 54.8 53.3 64.3 N.A. 43.9 43.9 25 40.7
Protein Similarity: 100 N.A. 98 63.5 N.A. 91.4 N.A. N.A. 70.4 73.1 73.9 79.8 N.A. 61 62.6 44.8 60
P-Site Identity: 100 N.A. 0 0 N.A. 0 N.A. N.A. 0 0 0 0 N.A. 0 0 0 0
P-Site Similarity: 100 N.A. 0 0 N.A. 0 N.A. N.A. 0 0 0 0 N.A. 0 0 0 0
Percent
Protein Identity: N.A. N.A. N.A. 28.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 100 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 100 0 0 0 0 0 0 0 0 100 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 100 0 0 0 0 0 0 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % I
% Lys: 100 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 100 0 0 0 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _