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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APH1B
All Species:
14.24
Human Site:
S98
Identified Species:
26.11
UniProt:
Q8WW43
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WW43
NP_112591.2
257
28460
S98
Y
K
L
L
K
K
A
S
E
G
L
K
S
I
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105067
257
28566
S98
Y
R
L
L
K
K
A
S
E
G
L
K
S
I
N
Dog
Lupus familis
XP_544714
346
38112
S187
Y
K
L
L
K
K
A
S
E
G
L
K
S
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8C7N7
257
28685
S98
Y
K
L
L
K
K
A
S
E
G
L
K
S
I
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514807
225
24964
L84
V
P
I
S
V
R
Q
L
S
Y
V
S
G
L
G
Chicken
Gallus gallus
XP_001233302
256
28091
E99
K
L
L
R
K
A
I
E
G
L
V
A
L
S
E
Frog
Xenopus laevis
NP_001089056
247
26905
E99
R
L
L
K
K
A
D
E
G
L
A
T
I
S
E
Zebra Danio
Brachydanio rerio
Q8JHE9
258
28628
E99
R
L
L
K
K
A
N
E
G
L
L
A
L
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQG2
238
26419
Q89
R
I
L
R
S
T
E
Q
G
L
H
A
V
A
E
Honey Bee
Apis mellifera
XP_392345
240
26608
E89
Y
W
V
L
R
K
A
E
R
G
L
D
K
V
T
Nematode Worm
Caenorhab. elegans
O45876
308
33529
G100
L
N
K
I
T
R
Q
G
Q
I
S
V
A
P
G
Sea Urchin
Strong. purpuratus
XP_783542
260
29305
Q105
T
T
P
E
Q
A
Q
Q
Q
A
Q
N
S
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L9G7
250
27517
S98
R
L
E
D
V
L
D
S
F
A
D
R
I
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.7
58
N.A.
84
N.A.
N.A.
58.7
54.8
53.3
64.3
N.A.
43.9
43.9
25
40.7
Protein Similarity:
100
N.A.
98
63.5
N.A.
91.4
N.A.
N.A.
70.4
73.1
73.9
79.8
N.A.
61
62.6
44.8
60
P-Site Identity:
100
N.A.
93.3
100
N.A.
100
N.A.
N.A.
0
13.3
13.3
20
N.A.
6.6
40
0
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
26.6
20
13.3
20
N.A.
6.6
60
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
31
39
0
0
16
8
24
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
16
0
0
0
8
8
0
0
0
% D
% Glu:
0
0
8
8
0
0
8
31
31
0
0
0
0
0
24
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
31
39
0
0
8
0
24
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
8
8
0
0
8
0
0
8
0
0
16
31
0
% I
% Lys:
8
24
8
16
54
39
0
0
0
0
0
31
8
0
0
% K
% Leu:
8
31
62
39
0
8
0
8
0
31
47
0
16
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
8
0
8
31
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
24
16
16
0
8
0
0
0
8
% Q
% Arg:
31
8
0
16
8
16
0
0
8
0
0
8
0
0
8
% R
% Ser:
0
0
0
8
8
0
0
39
8
0
8
8
39
31
0
% S
% Thr:
8
8
0
0
8
8
0
0
0
0
0
8
0
0
8
% T
% Val:
8
0
8
0
16
0
0
0
0
0
16
8
8
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
39
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _