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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APH1B
All Species:
11.21
Human Site:
Y70
Identified Species:
20.56
UniProt:
Q8WW43
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WW43
NP_112591.2
257
28460
Y70
K
D
G
P
T
Q
K
Y
L
L
I
F
G
A
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105067
257
28566
Y70
K
D
G
P
T
Q
K
Y
L
L
I
F
G
A
F
Dog
Lupus familis
XP_544714
346
38112
Y159
K
D
G
P
I
Q
K
Y
L
L
I
L
G
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C7N7
257
28685
Y70
R
D
G
P
V
Q
N
Y
L
L
I
F
G
V
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514807
225
24964
A56
I
Q
E
V
F
R
F
A
Y
Y
R
L
L
K
K
Chicken
Gallus gallus
XP_001233302
256
28091
L71
D
E
P
L
Q
K
G
L
L
I
F
G
V
M
F
Frog
Xenopus laevis
NP_001089056
247
26905
L71
D
A
N
L
Q
Y
G
L
L
I
F
G
A
A
V
Zebra Danio
Brachydanio rerio
Q8JHE9
258
28628
L71
S
A
T
Q
Q
R
G
L
L
I
F
G
V
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQG2
238
26419
F61
A
L
I
P
L
K
E
F
L
A
F
G
V
V
F
Honey Bee
Apis mellifera
XP_392345
240
26608
N61
Y
A
V
V
P
L
Q
N
H
L
A
F
G
L
V
Nematode Worm
Caenorhab. elegans
O45876
308
33529
I72
L
L
S
L
T
V
C
I
I
A
Q
E
L
S
R
Sea Urchin
Strong. purpuratus
XP_783542
260
29305
F77
S
I
L
F
Q
E
L
F
R
F
I
Y
Y
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L9G7
250
27517
L70
V
W
W
P
Y
A
L
L
V
I
T
S
V
C
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.7
58
N.A.
84
N.A.
N.A.
58.7
54.8
53.3
64.3
N.A.
43.9
43.9
25
40.7
Protein Similarity:
100
N.A.
98
63.5
N.A.
91.4
N.A.
N.A.
70.4
73.1
73.9
79.8
N.A.
61
62.6
44.8
60
P-Site Identity:
100
N.A.
100
73.3
N.A.
66.6
N.A.
N.A.
0
13.3
13.3
6.6
N.A.
20
20
6.6
6.6
P-Site Similarity:
100
N.A.
100
73.3
N.A.
73.3
N.A.
N.A.
6.6
33.3
20
20
N.A.
40
26.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
0
0
0
8
0
8
0
16
8
0
8
24
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
16
31
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
0
0
8
8
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
8
8
0
8
16
0
8
31
31
0
0
39
% F
% Gly:
0
0
31
0
0
0
24
0
0
0
0
31
39
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
8
0
8
0
0
8
8
31
39
0
0
0
8
% I
% Lys:
24
0
0
0
0
16
24
0
0
0
0
0
0
16
8
% K
% Leu:
8
16
8
24
8
8
16
31
62
39
0
16
16
8
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
47
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
31
31
8
0
0
0
8
0
0
0
0
% Q
% Arg:
8
0
0
0
0
16
0
0
8
0
8
0
0
0
8
% R
% Ser:
16
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% S
% Thr:
0
0
8
0
24
0
0
0
0
0
8
0
0
0
0
% T
% Val:
8
0
8
16
8
8
0
0
8
0
0
0
31
31
16
% V
% Trp:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
8
0
31
8
8
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _