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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED6
All Species:
10.61
Human Site:
T145
Identified Species:
29.17
UniProt:
Q8WW62
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WW62
NP_653277.1
240
27631
T145
V
F
Y
E
G
P
E
T
D
H
K
Q
K
E
R
Chimpanzee
Pan troglodytes
XP_001168712
240
27627
T145
V
F
Y
E
G
P
E
T
D
H
K
Q
K
E
R
Rhesus Macaque
Macaca mulatta
XP_001100588
240
27725
T145
V
F
Y
E
G
P
E
T
D
H
K
Q
K
E
R
Dog
Lupus familis
XP_853637
241
27900
M145
V
F
Y
E
G
P
E
M
D
H
K
Q
K
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQG0
239
27655
V145
V
F
Y
E
G
P
E
V
D
H
K
Q
S
Q
R
Rat
Rattus norvegicus
Q5BK85
227
25191
V134
S
F
Q
D
E
E
E
V
E
G
W
A
E
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510141
355
40282
M259
V
F
Y
E
G
F
D
M
D
H
E
E
K
T
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956697
225
25592
S132
N
M
G
E
D
E
E
S
E
D
W
K
A
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393466
227
26062
D134
V
I
R
Y
D
E
W
D
K
Y
T
R
E
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.6
90
N.A.
77.5
24.1
N.A.
50.9
N.A.
N.A.
23.3
N.A.
N.A.
25
N.A.
N.A.
Protein Similarity:
100
100
97.9
92.5
N.A.
86.6
41.6
N.A.
60.2
N.A.
N.A.
38.3
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
80
13.3
N.A.
53.3
N.A.
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
86.6
33.3
N.A.
73.3
N.A.
N.A.
33.3
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
12
12
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
23
0
12
12
67
12
0
0
0
0
0
% D
% Glu:
0
0
0
78
12
34
78
0
23
0
12
12
23
34
34
% E
% Phe:
0
78
0
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
67
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
12
0
56
12
56
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% L
% Met:
0
12
0
0
0
0
0
23
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
56
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
56
0
12
0
% Q
% Arg:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
45
% R
% Ser:
12
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% S
% Thr:
0
0
0
0
0
0
0
34
0
0
12
0
0
12
0
% T
% Val:
78
0
0
0
0
0
0
23
0
0
0
0
0
0
23
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
23
0
0
0
0
% W
% Tyr:
0
0
67
12
0
0
0
0
0
12
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _