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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIH1D2
All Species:
18.79
Human Site:
S223
Identified Species:
51.67
UniProt:
Q8WWB5
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWB5
NP_620144.1
315
35957
S223
C
L
I
E
E
I
S
S
T
E
I
Q
V
E
M
Chimpanzee
Pan troglodytes
XP_508754
315
35939
S223
C
L
I
E
E
I
S
S
T
E
I
Q
V
E
M
Rhesus Macaque
Macaca mulatta
XP_001107196
315
35969
S223
C
L
I
E
E
I
S
S
T
E
I
Q
V
E
I
Dog
Lupus familis
XP_536575
313
35766
E223
I
E
E
I
S
S
T
E
I
Q
V
E
M
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHR9
315
35565
S223
C
L
I
E
E
I
S
S
S
E
I
Q
V
E
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515441
220
23956
E131
Q
C
G
G
L
I
E
E
I
P
G
S
E
L
P
Chicken
Gallus gallus
XP_417932
328
36658
S232
Q
L
I
E
E
I
S
S
T
E
V
P
E
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5PRB3
322
36320
T230
L
I
E
V
I
S
S
T
E
L
D
Q
P
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783270
198
21928
E109
S
L
L
G
K
I
Q
E
L
S
N
Q
D
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94.9
83.1
N.A.
72.3
N.A.
N.A.
27.2
41.1
N.A.
39.4
N.A.
N.A.
N.A.
N.A.
21.2
Protein Similarity:
100
100
97.1
90.1
N.A.
84.7
N.A.
N.A.
43.4
60.6
N.A.
60.2
N.A.
N.A.
N.A.
N.A.
37.7
P-Site Identity:
100
100
93.3
0
N.A.
86.6
N.A.
N.A.
6.6
66.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
40
N.A.
100
N.A.
N.A.
6.6
80
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
45
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
12
% D
% Glu:
0
12
23
56
56
0
12
34
12
56
0
12
23
56
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
23
0
0
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
56
12
12
78
0
0
23
0
45
0
0
0
12
% I
% Lys:
0
0
0
0
12
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
12
67
12
0
12
0
0
0
12
12
0
0
0
23
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
23
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
0
12
12
0
23
% P
% Gln:
23
0
0
0
0
0
12
0
0
12
0
67
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
12
23
67
56
12
12
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
12
12
45
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
0
23
0
45
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _