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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIH1D2
All Species:
4.55
Human Site:
S244
Identified Species:
12.5
UniProt:
Q8WWB5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWB5
NP_620144.1
315
35957
S244
L
K
I
V
H
D
H
S
E
K
P
L
K
I
E
Chimpanzee
Pan troglodytes
XP_508754
315
35939
S244
L
K
I
V
H
D
H
S
E
K
P
L
K
I
E
Rhesus Macaque
Macaca mulatta
XP_001107196
315
35969
N244
L
K
I
V
H
D
H
N
E
K
P
L
K
T
E
Dog
Lupus familis
XP_536575
313
35766
K244
I
V
A
D
Q
K
E
K
P
Q
K
I
E
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHR9
315
35565
N244
L
K
V
V
K
D
R
N
E
K
P
L
K
I
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515441
220
23956
K152
A
Y
E
L
T
V
V
K
D
Q
D
G
R
S
V
Chicken
Gallus gallus
XP_417932
328
36658
N253
M
T
T
V
R
D
A
N
N
K
P
V
R
I
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5PRB3
322
36320
N251
L
T
I
C
P
D
G
N
G
S
S
R
I
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783270
198
21928
G130
R
L
Q
D
L
G
V
G
S
S
K
D
P
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94.9
83.1
N.A.
72.3
N.A.
N.A.
27.2
41.1
N.A.
39.4
N.A.
N.A.
N.A.
N.A.
21.2
Protein Similarity:
100
100
97.1
90.1
N.A.
84.7
N.A.
N.A.
43.4
60.6
N.A.
60.2
N.A.
N.A.
N.A.
N.A.
37.7
P-Site Identity:
100
100
86.6
6.6
N.A.
73.3
N.A.
N.A.
0
40
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
40
N.A.
86.6
N.A.
N.A.
26.6
66.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
23
0
67
0
0
12
0
12
12
0
0
0
% D
% Glu:
0
0
12
0
0
0
12
0
45
0
0
0
12
0
56
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
12
12
12
0
0
12
0
12
12
% G
% His:
0
0
0
0
34
0
34
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
45
0
0
0
0
0
0
0
0
12
12
56
0
% I
% Lys:
0
45
0
0
12
12
0
23
0
56
23
0
45
0
12
% K
% Leu:
56
12
0
12
12
0
0
0
0
0
0
45
0
12
0
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
45
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
0
0
12
0
56
0
12
0
0
% P
% Gln:
0
0
12
0
12
0
0
0
0
23
0
0
0
0
12
% Q
% Arg:
12
0
0
0
12
0
12
0
0
0
0
12
23
0
0
% R
% Ser:
0
0
0
0
0
0
0
23
12
23
12
0
0
12
0
% S
% Thr:
0
23
12
0
12
0
0
0
0
0
0
0
0
12
0
% T
% Val:
0
12
12
56
0
12
23
0
0
0
0
12
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _