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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNRF4 All Species: 11.21
Human Site: S368 Identified Species: 35.24
UniProt: Q8WWF5 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WWF5 NP_859061.3 429 46958 S368 S F D S T T Y S F R D E D P S
Chimpanzee Pan troglodytes XP_524065 420 45826 S359 S F D S T T D S F R D E D P S
Rhesus Macaque Macaca mulatta XP_001083609 429 46682 S368 S F D S T T D S F S D E D P S
Dog Lupus familis XP_542147 363 39659 S305 S F G D E D P S L P G H R P P
Cat Felis silvestris
Mouse Mus musculus Q91XF4 347 37996 Q289 E E Q E E E T Q E Q E E G D E
Rat Rattus norvegicus Q66HG0 380 42567 S322 S A S A R T Q S F G S L S E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518551 431 47607 Q361 D D Y E H G D Q L K I L P C S
Chicken Gallus gallus Q90972 381 42801 F323 A S V S T Q S F G A L S E S H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.7 90.4 62.4 N.A. 31.4 34.2 N.A. 39.4 34.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 93.9 92 68.3 N.A. 47.7 49.4 N.A. 54.5 50.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 86.6 26.6 N.A. 6.6 33.3 N.A. 6.6 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 86.6 26.6 N.A. 20 40 N.A. 13.3 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 13 0 13 0 0 0 0 0 13 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % C
% Asp: 13 13 38 13 0 13 38 0 0 0 38 0 38 13 0 % D
% Glu: 13 13 0 25 25 13 0 0 13 0 13 50 13 13 13 % E
% Phe: 0 50 0 0 0 0 0 13 50 0 0 0 0 0 0 % F
% Gly: 0 0 13 0 0 13 0 0 13 13 13 0 13 0 0 % G
% His: 0 0 0 0 13 0 0 0 0 0 0 13 0 0 13 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 25 0 13 25 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 13 0 0 13 0 0 13 50 13 % P
% Gln: 0 0 13 0 0 13 13 25 0 13 0 0 0 0 0 % Q
% Arg: 0 0 0 0 13 0 0 0 0 25 0 0 13 0 0 % R
% Ser: 63 13 13 50 0 0 13 63 0 13 13 13 13 13 63 % S
% Thr: 0 0 0 0 50 50 13 0 0 0 0 0 0 0 0 % T
% Val: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 13 0 0 0 13 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _