KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNRF4
All Species:
7.88
Human Site:
T418
Identified Species:
24.76
UniProt:
Q8WWF5
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWF5
NP_859061.3
429
46958
T418
S
L
E
A
E
Y
T
T
V
S
S
A
P
P
E
Chimpanzee
Pan troglodytes
XP_524065
420
45826
T409
S
L
E
V
E
V
T
T
V
S
S
A
P
P
E
Rhesus Macaque
Macaca mulatta
XP_001083609
429
46682
T418
S
L
E
A
E
D
T
T
V
S
P
A
P
P
E
Dog
Lupus familis
XP_542147
363
39659
E353
A
E
A
V
A
S
S
E
R
S
S
E
R
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91XF4
347
37996
D337
V
F
P
G
P
S
T
D
P
S
P
P
S
S
A
Rat
Rattus norvegicus
Q66HG0
380
42567
G370
V
V
Q
L
Q
P
N
G
E
P
D
Y
N
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518551
431
47607
K414
E
S
S
G
E
E
K
K
D
N
I
P
P
R
H
Chicken
Gallus gallus
Q90972
381
42801
D371
V
V
Q
L
Q
P
N
D
E
R
D
Y
R
V
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.7
90.4
62.4
N.A.
31.4
34.2
N.A.
39.4
34.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.9
92
68.3
N.A.
47.7
49.4
N.A.
54.5
50.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
86.6
20
N.A.
13.3
0
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
86.6
33.3
N.A.
13.3
20
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
13
25
13
0
0
0
0
0
0
38
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
0
25
13
0
25
0
0
0
0
% D
% Glu:
13
13
38
0
50
13
0
13
25
0
0
13
0
0
38
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
25
0
0
0
13
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
13
0
0
13
0
% I
% Lys:
0
0
0
0
0
0
13
13
0
0
0
0
0
0
0
% K
% Leu:
0
38
0
25
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
25
0
0
13
0
0
13
0
0
% N
% Pro:
0
0
13
0
13
25
0
0
13
13
25
25
50
50
13
% P
% Gln:
0
0
25
0
25
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
13
13
0
0
25
13
0
% R
% Ser:
38
13
13
0
0
25
13
0
0
63
38
0
13
13
0
% S
% Thr:
0
0
0
0
0
0
50
38
0
0
0
0
0
0
13
% T
% Val:
38
25
0
25
0
13
0
0
38
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
0
0
0
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _