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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNE4 All Species: 15.15
Human Site: S23 Identified Species: 37.04
UniProt: Q8WWG9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WWG9 NP_542402.2 170 18439 S23 A S S S P L E S R A A G G G S
Chimpanzee Pan troglodytes XP_001166586 221 23776 S74 A S S S P L E S R A A G G G S
Rhesus Macaque Macaca mulatta XP_001108426 170 18519 S23 A S S S P L E S R A P G G G N
Dog Lupus familis XP_545668 170 18574 S23 A P S S H L V S H V P G S E S
Cat Felis silvestris
Mouse Mus musculus Q9WTW3 170 18620 S23 A S S S P L E S H V P S N S S
Rat Rattus norvegicus P15383 130 14680
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512319 456 50338 A309 N S T Q N I P A Q P S Q Q S S
Chicken Gallus gallus XP_001234563 160 17777 S17 M L N A E S R S T E K N N G N
Frog Xenopus laevis NP_001082344 105 12158
Zebra Danio Brachydanio rerio NP_001076366 166 18038 G22 N S R I P L S G G S D N N A Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.5 97.6 91.1 N.A. 89.4 25.2 N.A. 28.2 70.5 20 39.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 76.9 98.8 93.5 N.A. 94.1 37.6 N.A. 32.4 78.8 30 55.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 46.6 N.A. 60 0 N.A. 13.3 13.3 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 46.6 N.A. 60 0 N.A. 46.6 33.3 0 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 0 10 0 0 0 10 0 30 20 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 40 0 0 10 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 10 0 0 40 30 40 0 % G
% His: 0 0 0 0 10 0 0 0 20 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 10 0 0 0 60 0 0 0 0 0 0 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 20 0 10 0 10 0 0 0 0 0 0 20 30 0 20 % N
% Pro: 0 10 0 0 50 0 10 0 0 10 30 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 10 0 0 10 10 0 0 % Q
% Arg: 0 0 10 0 0 0 10 0 30 0 0 0 0 0 0 % R
% Ser: 0 60 50 50 0 10 10 60 0 10 10 10 10 20 50 % S
% Thr: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 10 0 0 20 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _