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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNE4
All Species:
22.73
Human Site:
Y73
Identified Species:
55.56
UniProt:
Q8WWG9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWG9
NP_542402.2
170
18439
Y73
K
S
S
L
L
L
L
Y
K
D
E
E
R
L
W
Chimpanzee
Pan troglodytes
XP_001166586
221
23776
Y124
K
S
S
L
L
L
L
Y
K
D
E
E
R
L
W
Rhesus Macaque
Macaca mulatta
XP_001108426
170
18519
Y73
K
S
S
L
L
L
L
Y
K
D
E
E
R
L
W
Dog
Lupus familis
XP_545668
170
18574
Y73
K
S
S
L
L
L
L
Y
K
D
E
E
R
L
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTW3
170
18620
Y73
K
S
S
L
L
L
L
Y
K
D
E
E
R
L
W
Rat
Rattus norvegicus
P15383
130
14680
L37
D
L
A
R
R
S
Q
L
R
D
D
S
K
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512319
456
50338
Y359
K
S
S
L
L
L
L
Y
Q
D
E
E
R
L
W
Chicken
Gallus gallus
XP_001234563
160
17777
E67
L
L
L
Y
K
D
E
E
R
E
W
G
E
A
V
Frog
Xenopus laevis
NP_001082344
105
12158
L12
N
T
S
R
L
R
S
L
L
T
Q
L
L
Q
E
Zebra Danio
Brachydanio rerio
NP_001076366
166
18038
E72
T
R
L
L
H
E
E
E
Q
R
E
W
G
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.5
97.6
91.1
N.A.
89.4
25.2
N.A.
28.2
70.5
20
39.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
76.9
98.8
93.5
N.A.
94.1
37.6
N.A.
32.4
78.8
30
55.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
93.3
0
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
100
13.3
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
0
0
0
70
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
20
20
0
10
70
60
10
0
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
60
0
0
0
10
0
0
0
50
0
0
0
10
0
0
% K
% Leu:
10
20
20
70
70
60
60
20
10
0
0
10
10
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
20
0
10
0
0
10
0
% Q
% Arg:
0
10
0
20
10
10
0
0
20
10
0
0
60
0
10
% R
% Ser:
0
60
70
0
0
10
10
0
0
0
0
10
0
0
0
% S
% Thr:
10
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
60
% W
% Tyr:
0
0
0
10
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _