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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPIRE2
All Species:
13.03
Human Site:
S380
Identified Species:
40.95
UniProt:
Q8WWL2
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWL2
NP_115827.1
714
79598
S380
P
C
I
L
N
A
C
S
G
D
A
K
S
T
S
Chimpanzee
Pan troglodytes
XP_511239
622
69289
P304
M
V
D
G
D
I
P
P
R
V
K
K
D
A
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536746
626
70825
D308
C
I
N
L
S
I
T
D
A
G
N
N
S
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1S6
718
80191
S383
P
C
I
L
N
A
C
S
G
D
I
K
S
T
S
Rat
Rattus norvegicus
NP_001121010
714
79682
S384
P
C
I
L
N
A
C
S
G
D
I
K
S
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510997
694
77874
S327
P
C
L
L
N
A
C
S
G
D
A
K
S
T
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U3H9
606
68115
E288
P
F
N
P
L
P
T
E
F
S
L
T
P
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1K1
1020
114849
Q551
A
E
M
H
R
C
S
Q
P
K
M
P
P
Y
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
N.A.
76
N.A.
84.8
85.4
N.A.
68.6
N.A.
N.A.
43.2
N.A.
24.4
N.A.
N.A.
N.A.
Protein Similarity:
100
85.8
N.A.
79.6
N.A.
89.2
90
N.A.
78
N.A.
N.A.
55.8
N.A.
38.7
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
N.A.
13.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
N.A.
20
N.A.
93.3
93.3
N.A.
100
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
50
0
0
13
0
25
0
0
13
0
% A
% Cys:
13
50
0
0
0
13
50
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
13
0
0
13
0
50
0
0
13
0
0
% D
% Glu:
0
13
0
0
0
0
0
13
0
0
0
0
0
0
13
% E
% Phe:
0
13
0
0
0
0
0
0
13
0
0
0
0
13
0
% F
% Gly:
0
0
0
13
0
0
0
0
50
13
0
0
0
0
0
% G
% His:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
13
% H
% Ile:
0
13
38
0
0
25
0
0
0
0
25
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
13
13
63
0
0
0
% K
% Leu:
0
0
13
63
13
0
0
0
0
0
13
0
0
0
0
% L
% Met:
13
0
13
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
25
0
50
0
0
0
0
0
13
13
0
0
0
% N
% Pro:
63
0
0
13
0
13
13
13
13
0
0
13
25
0
13
% P
% Gln:
0
0
0
0
0
0
0
13
0
0
0
0
0
13
0
% Q
% Arg:
0
0
0
0
13
0
0
0
13
0
0
0
0
0
13
% R
% Ser:
0
0
0
0
13
0
13
50
0
13
0
0
63
0
50
% S
% Thr:
0
0
0
0
0
0
25
0
0
0
0
13
0
50
0
% T
% Val:
0
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _