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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HPSE2 All Species: 4.55
Human Site: S16 Identified Species: 11.11
UniProt: Q8WWQ2 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WWQ2 NP_068600.3 592 66596 S16 E A M P S S N S R P P A C L A
Chimpanzee Pan troglodytes XP_517183 543 61209 P11 R S K P A L P P P L M L L L L
Rhesus Macaque Macaca mulatta XP_001104975 545 61334 P11 R S K P A L P P P P P L L L L
Dog Lupus familis XP_850311 592 66752 S16 E A M P S S N S R P P A C L A
Cat Felis silvestris
Mouse Mus musculus Q6YGZ1 535 60032 G11 L L L L W L W G P L G A L A Q
Rat Rattus norvegicus Q71RP1 536 60461 W11 P L L L L W L W G R L G A L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90YK5 523 58368 L9 L V L L L L V L L L A V P P R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_691045 577 65466 R31 I S S A V T Y R R P V S G G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791694 477 53110
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FF10 543 60232 L17 V F L G C L L L V P E K T M A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.2 43.4 98.8 N.A. 43.5 43.2 N.A. N.A. 40.7 N.A. 73.3 N.A. N.A. N.A. N.A. 26.5
Protein Similarity: 100 58.7 59.7 98.9 N.A. 58.2 59.4 N.A. N.A. 53.7 N.A. 83.6 N.A. N.A. N.A. N.A. 40.2
P-Site Identity: 100 13.3 26.6 100 N.A. 6.6 6.6 N.A. N.A. 0 N.A. 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 26.6 40 100 N.A. 13.3 13.3 N.A. N.A. 6.6 N.A. 33.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 24.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 41.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 10 20 0 0 0 0 0 10 30 10 10 30 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 20 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 20 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 10 10 0 10 10 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 20 0 0 0 0 0 0 0 0 10 0 0 10 % K
% Leu: 20 20 40 30 20 50 20 20 10 30 10 20 30 50 20 % L
% Met: 0 0 20 0 0 0 0 0 0 0 10 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 40 0 0 20 20 30 50 30 0 10 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 20 0 0 0 0 0 0 10 30 10 0 0 0 0 10 % R
% Ser: 0 30 10 0 20 20 0 20 0 0 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 10 % T
% Val: 10 10 0 0 10 0 10 0 10 0 10 10 0 0 0 % V
% Trp: 0 0 0 0 10 10 10 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _