KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPSE2
All Species:
14.24
Human Site:
S277
Identified Species:
34.81
UniProt:
Q8WWQ2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWQ2
NP_068600.3
592
66596
S277
H
G
R
A
V
N
G
S
Q
L
G
K
D
Y
I
Chimpanzee
Pan troglodytes
XP_517183
543
61209
S240
A
D
I
F
I
N
G
S
Q
L
G
E
D
F
I
Rhesus Macaque
Macaca mulatta
XP_001104975
545
61334
S242
A
D
I
F
I
N
G
S
Q
L
G
E
D
F
I
Dog
Lupus familis
XP_850311
592
66752
S277
H
G
R
A
V
N
G
S
Q
L
G
K
D
Y
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6YGZ1
535
60032
V239
S
Q
L
G
E
D
F
V
E
L
H
K
L
L
Q
Rat
Rattus norvegicus
Q71RP1
536
60461
F239
G
L
Q
L
G
E
D
F
V
E
L
H
K
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YK5
523
58368
L237
Q
L
L
S
Q
H
P
L
Y
R
H
A
E
L
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691045
577
65466
S263
A
A
R
S
V
N
S
S
R
L
A
Q
D
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791694
477
53110
P191
N
T
S
S
I
P
S
P
S
A
S
Y
L
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF10
543
60232
Q250
A
P
G
G
F
Y
E
Q
Q
W
Y
T
K
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
43.4
98.8
N.A.
43.5
43.2
N.A.
N.A.
40.7
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
100
58.7
59.7
98.9
N.A.
58.2
59.4
N.A.
N.A.
53.7
N.A.
83.6
N.A.
N.A.
N.A.
N.A.
40.2
P-Site Identity:
100
53.3
53.3
100
N.A.
13.3
0
N.A.
N.A.
0
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
73.3
73.3
100
N.A.
26.6
13.3
N.A.
N.A.
20
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
10
0
20
0
0
0
0
0
10
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
10
10
0
0
0
0
0
50
0
0
% D
% Glu:
0
0
0
0
10
10
10
0
10
10
0
20
10
0
10
% E
% Phe:
0
0
0
20
10
0
10
10
0
0
0
0
0
20
0
% F
% Gly:
10
20
10
20
10
0
40
0
0
0
40
0
0
0
0
% G
% His:
20
0
0
0
0
10
0
0
0
0
20
10
0
0
0
% H
% Ile:
0
0
20
0
30
0
0
0
0
0
0
0
0
0
40
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
30
20
0
0
% K
% Leu:
0
20
20
10
0
0
0
10
0
60
10
0
20
40
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
50
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
10
0
0
0
10
10
10
0
0
0
0
0
0
0
% P
% Gln:
10
10
10
0
10
0
0
10
50
0
0
10
0
0
10
% Q
% Arg:
0
0
30
0
0
0
0
0
10
10
0
0
0
0
0
% R
% Ser:
10
0
10
30
0
0
20
50
10
0
10
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% T
% Val:
0
0
0
0
30
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
10
0
10
10
0
30
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _