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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPSE2
All Species:
16.36
Human Site:
T356
Identified Species:
40
UniProt:
Q8WWQ2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWQ2
NP_068600.3
592
66596
T356
L
K
T
R
L
L
D
T
L
S
D
Q
I
R
K
Chimpanzee
Pan troglodytes
XP_517183
543
61209
I318
L
N
P
D
V
L
D
I
F
I
S
S
V
Q
K
Rhesus Macaque
Macaca mulatta
XP_001104975
545
61334
I320
L
N
P
D
V
L
D
I
F
I
S
S
V
Q
K
Dog
Lupus familis
XP_850311
592
66752
T356
L
K
T
R
L
L
D
T
L
S
D
Q
I
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6YGZ1
535
60032
T310
L
S
S
D
V
L
D
T
F
I
L
S
V
Q
K
Rat
Rattus norvegicus
Q71RP1
536
60461
T311
L
S
S
D
V
L
D
T
F
I
L
S
V
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YK5
523
58368
L307
A
T
A
I
H
D
V
L
G
I
V
E
A
T
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691045
577
65466
T342
M
K
T
R
L
L
D
T
L
S
E
Q
I
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791694
477
53110
S261
S
K
I
W
I
T
E
S
G
V
C
F
G
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF10
543
60232
S321
A
S
P
W
V
G
E
S
G
G
A
Y
N
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
43.4
98.8
N.A.
43.5
43.2
N.A.
N.A.
40.7
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
100
58.7
59.7
98.9
N.A.
58.2
59.4
N.A.
N.A.
53.7
N.A.
83.6
N.A.
N.A.
N.A.
N.A.
40.2
P-Site Identity:
100
26.6
26.6
100
N.A.
33.3
33.3
N.A.
N.A.
0
N.A.
80
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
46.6
46.6
100
N.A.
60
60
N.A.
N.A.
6.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
10
0
0
0
0
0
0
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
40
0
10
70
0
0
0
20
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
20
0
0
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
40
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
30
10
0
0
10
0
20
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
10
0
0
20
0
50
0
0
30
0
0
% I
% Lys:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
70
% K
% Leu:
60
0
0
0
30
70
0
10
30
0
20
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
30
0
40
0
% Q
% Arg:
0
0
0
30
0
0
0
0
0
0
0
0
0
20
0
% R
% Ser:
10
30
20
0
0
0
0
20
0
30
20
40
0
20
0
% S
% Thr:
0
10
30
0
0
10
0
50
0
0
0
0
0
20
0
% T
% Val:
0
0
0
0
50
0
10
0
0
10
10
0
40
0
10
% V
% Trp:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _