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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPSE2
All Species:
5.76
Human Site:
Y142
Identified Species:
14.07
UniProt:
Q8WWQ2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWQ2
NP_068600.3
592
66596
Y142
R
G
G
P
G
P
D
Y
Y
L
K
N
Y
E
D
Chimpanzee
Pan troglodytes
XP_517183
543
61209
I132
D
I
C
K
Y
G
S
I
P
P
D
V
E
E
K
Rhesus Macaque
Macaca mulatta
XP_001104975
545
61334
G132
N
Q
D
I
C
K
S
G
S
I
P
P
D
V
E
Dog
Lupus familis
XP_850311
592
66752
Y142
R
G
G
P
G
P
D
Y
Y
L
K
N
Y
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6YGZ1
535
60032
L132
S
A
A
V
L
R
K
L
Q
V
E
W
P
F
Q
Rat
Rattus norvegicus
Q71RP1
536
60461
K132
V
S
A
D
V
L
R
K
L
Q
M
E
W
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YK5
523
58368
L130
W
P
L
Q
E
K
L
L
L
A
E
H
S
W
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691045
577
65466
L152
D
K
Q
K
G
C
K
L
A
S
H
P
D
M
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791694
477
53110
N84
A
H
T
W
D
N
I
N
E
F
A
R
S
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF10
543
60232
S143
K
R
W
D
E
L
N
S
F
L
T
A
T
G
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
43.4
98.8
N.A.
43.5
43.2
N.A.
N.A.
40.7
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
100
58.7
59.7
98.9
N.A.
58.2
59.4
N.A.
N.A.
53.7
N.A.
83.6
N.A.
N.A.
N.A.
N.A.
40.2
P-Site Identity:
100
6.6
0
100
N.A.
0
0
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
13.3
100
N.A.
13.3
6.6
N.A.
N.A.
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
20
0
0
0
0
0
10
10
10
10
0
0
10
% A
% Cys:
0
0
10
0
10
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
10
20
10
0
20
0
0
0
10
0
20
0
20
% D
% Glu:
0
0
0
0
20
0
0
0
10
0
20
10
10
30
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
10
% F
% Gly:
0
20
20
0
30
10
0
10
0
0
0
0
0
10
10
% G
% His:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
0
% H
% Ile:
0
10
0
10
0
0
10
10
0
10
0
0
0
0
0
% I
% Lys:
10
10
0
20
0
20
20
10
0
0
20
0
0
0
20
% K
% Leu:
0
0
10
0
10
20
10
30
20
30
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
10
% M
% Asn:
10
0
0
0
0
10
10
10
0
0
0
20
0
0
0
% N
% Pro:
0
10
0
20
0
20
0
0
10
10
10
20
10
10
0
% P
% Gln:
0
10
10
10
0
0
0
0
10
10
0
0
0
0
10
% Q
% Arg:
20
10
0
0
0
10
10
0
0
0
0
10
0
0
0
% R
% Ser:
10
10
0
0
0
0
20
10
10
10
0
0
20
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
10
0
10
0
0
% T
% Val:
10
0
0
10
10
0
0
0
0
10
0
10
0
20
0
% V
% Trp:
10
0
10
10
0
0
0
0
0
0
0
10
10
10
0
% W
% Tyr:
0
0
0
0
10
0
0
20
20
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _