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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPSE2
All Species:
12.42
Human Site:
Y211
Identified Species:
30.37
UniProt:
Q8WWQ2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWQ2
NP_068600.3
592
66596
Y211
A
R
S
L
D
K
L
Y
N
F
A
D
C
S
G
Chimpanzee
Pan troglodytes
XP_517183
543
61209
A177
V
D
V
L
Y
T
F
A
N
C
S
G
L
D
L
Rhesus Macaque
Macaca mulatta
XP_001104975
545
61334
Y176
R
S
S
V
D
M
L
Y
T
F
A
N
C
S
G
Dog
Lupus familis
XP_850311
592
66752
Y211
A
R
S
L
D
K
L
Y
N
F
A
D
C
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6YGZ1
535
60032
L176
A
K
C
S
G
L
D
L
I
F
G
L
N
A
L
Rat
Rattus norvegicus
Q71RP1
536
60461
D176
F
A
K
C
S
R
L
D
L
I
F
G
L
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YK5
523
58368
A174
L
N
A
L
L
R
R
A
G
L
Q
W
D
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691045
577
65466
Y197
A
R
S
L
D
K
L
Y
N
F
A
D
C
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791694
477
53110
L128
K
Q
R
G
Y
P
V
L
W
A
L
G
N
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF10
543
60232
V187
Q
D
F
L
N
Y
T
V
S
K
G
Y
V
I
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
43.4
98.8
N.A.
43.5
43.2
N.A.
N.A.
40.7
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
100
58.7
59.7
98.9
N.A.
58.2
59.4
N.A.
N.A.
53.7
N.A.
83.6
N.A.
N.A.
N.A.
N.A.
40.2
P-Site Identity:
100
13.3
60
100
N.A.
13.3
6.6
N.A.
N.A.
13.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
73.3
100
N.A.
26.6
20
N.A.
N.A.
26.6
N.A.
100
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
10
10
0
0
0
0
20
0
10
40
0
0
20
10
% A
% Cys:
0
0
10
10
0
0
0
0
0
10
0
0
40
0
0
% C
% Asp:
0
20
0
0
40
0
10
10
0
0
0
30
10
10
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
10
0
10
0
0
0
10
0
0
50
10
0
0
0
0
% F
% Gly:
0
0
0
10
10
0
0
0
10
0
20
30
0
0
40
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% I
% Lys:
10
10
10
0
0
30
0
0
0
10
0
0
0
0
0
% K
% Leu:
10
0
0
60
10
10
50
20
10
10
10
10
20
0
20
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
0
40
0
0
10
20
10
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
10
30
10
0
0
20
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
40
10
10
0
0
0
10
0
10
0
0
40
10
% S
% Thr:
0
0
0
0
0
10
10
0
10
0
0
0
0
0
0
% T
% Val:
10
0
10
10
0
0
10
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
20
10
0
40
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _