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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPSE2
All Species:
27.58
Human Site:
Y442
Identified Species:
67.41
UniProt:
Q8WWQ2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWQ2
NP_068600.3
592
66596
Y442
N
F
N
P
L
P
D
Y
W
L
S
L
L
Y
K
Chimpanzee
Pan troglodytes
XP_517183
543
61209
Y404
N
F
D
P
L
P
D
Y
W
L
S
L
L
F
K
Rhesus Macaque
Macaca mulatta
XP_001104975
545
61334
Y406
N
F
D
P
L
P
D
Y
W
L
S
L
L
F
K
Dog
Lupus familis
XP_850311
592
66752
Y442
N
F
N
P
L
P
D
Y
W
L
S
L
L
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6YGZ1
535
60032
Y396
N
F
E
P
L
P
D
Y
W
L
S
L
L
F
K
Rat
Rattus norvegicus
Q71RP1
536
60461
Y397
N
F
E
P
L
P
D
Y
W
L
S
L
L
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YK5
523
58368
R392
W
L
S
L
L
Y
K
R
L
V
G
T
R
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691045
577
65466
Y428
N
F
N
P
L
P
D
Y
W
V
S
L
L
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791694
477
53110
R346
K
V
V
S
T
K
V
R
T
S
R
E
E
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF10
543
60232
Y409
G
P
P
Q
L
R
V
Y
A
H
C
S
K
G
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
43.4
98.8
N.A.
43.5
43.2
N.A.
N.A.
40.7
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
100
58.7
59.7
98.9
N.A.
58.2
59.4
N.A.
N.A.
53.7
N.A.
83.6
N.A.
N.A.
N.A.
N.A.
40.2
P-Site Identity:
100
86.6
86.6
100
N.A.
86.6
86.6
N.A.
N.A.
6.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
20
N.A.
100
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
20
0
0
0
70
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
20
0
0
0
0
0
0
0
0
10
10
0
0
% E
% Phe:
0
70
0
0
0
0
0
0
0
0
0
0
0
50
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
10
0
0
0
0
0
10
0
70
% K
% Leu:
0
10
0
10
90
0
0
0
10
60
0
70
70
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
70
0
30
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
10
10
70
0
70
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
20
0
0
10
0
10
0
10
% R
% Ser:
0
0
10
10
0
0
0
0
0
10
70
10
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
10
0
0
10
0
0
0
% T
% Val:
0
10
10
0
0
0
20
0
0
20
0
0
0
10
0
% V
% Trp:
10
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
80
0
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _