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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAB3 All Species: 16.97
Human Site: S379 Identified Species: 41.48
UniProt: Q8WWW8 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WWW8 NP_001075042.1 586 65589 S379 L N L P C R F S P M Y P T A S
Chimpanzee Pan troglodytes XP_529211 586 65556 S379 L N L P C R F S P M Y P T A S
Rhesus Macaque Macaca mulatta XP_001095912 586 65776 S379 L N L P C R F S P M Y P T A S
Dog Lupus familis XP_549381 622 68656 S415 L N L P R R L S P A R P P A C
Cat Felis silvestris
Mouse Mus musculus Q8BSM5 595 67822 K379 L S L N L P C K F S P I Y P T
Rat Rattus norvegicus Q9EQH1 665 73310 A381 E N S R S V A A T I P R R N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509543 623 69506 T404 L N L P C R F T P L Y S S T S
Chicken Gallus gallus XP_426275 601 66883 C379 R L S L N L P C R F S P L Y S
Frog Xenopus laevis NP_001089201 691 76011 N449 N Y V P M N P N S P P R Q H S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ9 878 95517 S426 L R E N V D R S T R P S D S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.7 41.6 N.A. 76.6 33 N.A. 63.2 66.5 28.5 N.A. N.A. 23 N.A. N.A. N.A.
Protein Similarity: 100 100 98.4 51.9 N.A. 85.5 50.8 N.A. 73 77.3 47.4 N.A. N.A. 36.9 N.A. N.A. N.A.
P-Site Identity: 100 100 100 60 N.A. 13.3 6.6 N.A. 66.6 13.3 13.3 N.A. N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 60 N.A. 26.6 26.6 N.A. 86.6 13.3 26.6 N.A. N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 10 0 10 0 0 0 40 0 % A
% Cys: 0 0 0 0 40 0 10 10 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % D
% Glu: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 40 0 10 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 70 10 60 10 10 10 10 0 0 10 0 0 10 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 30 0 0 0 0 0 % M
% Asn: 10 60 0 20 10 10 0 10 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 60 0 10 20 0 50 10 40 50 10 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 10 10 0 10 10 50 10 0 10 10 10 20 10 0 0 % R
% Ser: 0 10 20 0 10 0 0 50 10 10 10 20 10 10 70 % S
% Thr: 0 0 0 0 0 0 0 10 20 0 0 0 30 10 20 % T
% Val: 0 0 10 0 10 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 40 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _