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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
13.64
Human Site:
S145
Identified Species:
20
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
S145
T
V
K
E
L
G
N
S
L
D
K
C
K
N
N
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
W55
V
K
T
I
A
K
L
W
D
S
K
M
F
A
E
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
A132
E
L
E
R
L
E
E
A
C
D
M
A
L
E
L
Dog
Lupus familis
XP_850917
499
55424
S145
T
V
K
E
L
G
N
S
L
D
K
C
K
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
S145
T
V
K
E
L
G
N
S
L
D
K
C
K
N
N
Rat
Rattus norvegicus
NP_001099689
499
55397
S145
T
V
K
E
L
G
N
S
L
D
K
C
K
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
A86
E
V
L
G
P
V
E
A
A
P
E
Y
R
V
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
N144
T
V
K
E
L
G
N
N
L
D
K
C
K
N
N
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
N156
T
V
K
E
L
G
N
N
L
E
K
C
K
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
D153
A
V
K
E
L
G
N
D
L
D
Q
V
K
N
N
Honey Bee
Apis mellifera
XP_394383
488
54294
D142
T
V
R
E
L
G
N
D
L
D
R
A
K
N
N
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
E154
T
V
Q
L
L
G
N
E
I
N
S
K
V
V
K
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
D143
T
V
K
E
L
G
N
D
L
E
R
A
K
N
N
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
E147
V
V
K
K
I
G
N
E
M
D
L
T
L
V
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
E147
V
I
S
I
L
E
N
E
N
Y
S
K
N
E
S
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
G215
A
R
I
I
V
T
M
G
M
R
S
N
A
T
T
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
6.6
13.3
100
N.A.
100
100
N.A.
6.6
N.A.
93.3
86.6
N.A.
73.3
73.3
33.3
73.3
P-Site Similarity:
100
6.6
33.3
100
N.A.
100
100
N.A.
26.6
N.A.
100
100
N.A.
80
86.6
53.3
86.6
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
33.3
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
60
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
7
0
0
13
7
0
0
19
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
38
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
19
7
57
0
0
0
0
7
% D
% Glu:
13
0
7
57
0
13
13
19
0
13
7
0
0
13
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
7
0
69
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
19
7
0
0
0
7
0
0
0
0
0
7
% I
% Lys:
0
7
57
7
0
7
0
0
0
0
44
13
57
0
7
% K
% Leu:
0
7
7
7
75
0
7
0
57
0
7
0
13
0
7
% L
% Met:
0
0
0
0
0
0
7
0
13
0
7
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
75
13
7
7
0
7
7
57
57
% N
% Pro:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
7
7
7
0
0
0
0
0
7
13
0
7
0
0
% R
% Ser:
0
0
7
0
0
0
0
25
0
7
19
0
0
0
7
% S
% Thr:
57
0
7
0
0
7
0
0
0
0
0
7
0
7
7
% T
% Val:
19
75
0
0
7
7
0
0
0
0
0
7
7
19
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _