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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
33.94
Human Site:
S180
Identified Species:
49.78
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
S180
T
T
Q
G
Q
Q
L
S
E
E
E
L
E
R
L
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
Y90
P
V
E
A
A
P
E
Y
R
V
I
V
D
A
N
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
A167
N
L
S
I
I
I
G
A
S
T
A
A
K
I
M
Dog
Lupus familis
XP_850917
499
55424
S180
T
T
Q
G
Q
Q
L
S
E
E
E
L
E
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
S180
T
T
Q
G
Q
Q
L
S
D
E
E
L
E
R
L
Rat
Rattus norvegicus
NP_001099689
499
55397
S180
T
T
Q
G
Q
Q
L
S
D
E
E
L
E
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
R121
I
R
D
K
Y
S
K
R
F
P
E
L
E
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
T179
T
T
Q
G
Q
Q
L
T
D
E
E
L
E
R
I
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
G191
T
T
Q
G
T
M
L
G
D
D
E
L
Q
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
T188
T
T
Q
G
T
M
L
T
P
A
E
K
A
K
I
Honey Bee
Apis mellifera
XP_394383
488
54294
T177
T
T
Q
G
Q
L
L
T
E
E
E
K
E
A
I
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
E189
T
T
Q
G
V
K
L
E
P
N
E
L
E
T
V
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
T178
T
T
Q
G
T
P
L
T
Q
Q
E
L
A
T
V
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
E182
S
G
K
P
L
P
E
E
V
L
Q
K
T
I
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
S182
L
T
M
S
M
K
T
S
F
K
N
K
E
P
L
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
S250
I
S
M
G
T
E
V
S
E
E
D
L
Q
N
I
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
0
0
100
N.A.
93.3
93.3
N.A.
26.6
N.A.
80
60
N.A.
40
66.6
53.3
46.6
P-Site Similarity:
100
20
20
100
N.A.
100
100
N.A.
26.6
N.A.
100
80
N.A.
60
80
66.6
73.3
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
0
N.A.
N.A.
N.A.
26.6
33.3
P-Site Similarity:
20
N.A.
N.A.
N.A.
40
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
0
0
7
0
7
7
7
13
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
25
7
7
0
7
0
0
% D
% Glu:
0
0
7
0
0
7
13
13
25
44
69
0
57
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% F
% Gly:
0
7
0
69
0
0
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
7
7
7
0
0
0
0
7
0
0
13
25
% I
% Lys:
0
0
7
7
0
13
7
0
0
7
0
25
7
7
0
% K
% Leu:
7
7
0
0
7
7
63
0
0
7
0
63
0
0
44
% L
% Met:
0
0
13
0
7
13
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
0
0
0
0
0
0
0
0
7
7
0
0
7
7
% N
% Pro:
7
0
0
7
0
19
0
0
13
7
0
0
0
7
0
% P
% Gln:
0
0
63
0
38
32
0
0
7
7
7
0
13
0
0
% Q
% Arg:
0
7
0
0
0
0
0
7
7
0
0
0
0
38
0
% R
% Ser:
7
7
7
7
0
7
0
38
7
0
0
0
0
7
0
% S
% Thr:
63
69
0
0
25
0
7
25
0
7
0
0
7
13
0
% T
% Val:
0
7
0
0
7
0
7
0
7
7
0
7
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _