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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
35.15
Human Site:
S213
Identified Species:
51.56
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
S213
E
Y
V
E
S
R
M
S
F
I
A
P
N
L
S
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
Y118
H
K
F
I
R
D
K
Y
S
K
R
F
P
E
L
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
G195
A
C
N
I
M
L
L
G
A
Q
R
K
T
L
S
Dog
Lupus familis
XP_850917
499
55424
S213
E
Y
V
E
S
R
M
S
F
I
A
P
N
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
S213
E
Y
V
E
S
R
M
S
F
I
A
P
N
L
S
Rat
Rattus norvegicus
NP_001099689
499
55397
S213
E
Y
V
E
S
R
M
S
F
I
A
P
N
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
C149
L
G
N
S
L
D
K
C
K
N
N
E
N
L
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
S212
E
Y
V
E
S
R
M
S
F
I
A
P
N
L
S
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
S224
E
Y
V
E
S
R
M
S
F
I
A
P
N
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
T221
E
Y
V
E
S
R
M
T
F
I
A
P
N
L
S
Honey Bee
Apis mellifera
XP_394383
488
54294
A210
E
Y
V
E
S
R
M
A
F
I
A
P
N
L
S
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
A222
Q
L
V
E
W
R
M
A
L
I
A
P
N
L
V
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
S211
T
Y
V
E
S
R
M
S
F
I
A
P
N
L
S
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
G213
D
F
V
E
T
R
M
G
Y
I
A
P
N
L
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
S223
Q
Y
I
A
S
K
I
S
I
I
A
P
N
V
C
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
R283
D
Y
L
E
N
R
M
R
A
I
A
P
N
M
T
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
0
13.3
100
N.A.
100
100
N.A.
13.3
N.A.
100
100
N.A.
93.3
93.3
60
93.3
P-Site Similarity:
100
0
20
100
N.A.
100
100
N.A.
13.3
N.A.
100
100
N.A.
100
100
73.3
93.3
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
66.6
N.A.
N.A.
N.A.
46.6
53.3
P-Site Similarity:
93.3
N.A.
N.A.
N.A.
80
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
13
13
0
82
0
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
7
% C
% Asp:
13
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% D
% Glu:
50
0
0
75
0
0
0
0
0
0
0
7
0
7
0
% E
% Phe:
0
7
7
0
0
0
0
0
57
0
0
7
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
13
0
0
0
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
13
0
0
7
0
7
82
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
7
13
0
7
7
0
7
0
0
0
% K
% Leu:
7
7
7
0
7
7
7
0
7
0
0
0
0
82
7
% L
% Met:
0
0
0
0
7
0
75
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
13
0
7
0
0
0
0
7
7
0
88
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
82
7
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% Q
% Arg:
0
0
0
0
7
75
0
7
0
0
13
0
0
0
0
% R
% Ser:
0
0
0
7
63
0
0
50
7
0
0
0
0
0
69
% S
% Thr:
7
0
0
0
7
0
0
7
0
0
0
0
7
0
7
% T
% Val:
0
0
69
0
0
0
0
0
0
0
0
0
0
7
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
69
0
0
0
0
0
7
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _