KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
41.21
Human Site:
S263
Identified Species:
60.44
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
S263
R
K
T
L
S
G
F
S
S
T
S
V
L
P
H
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
V167
T
N
A
T
I
M
V
V
S
V
T
A
S
T
T
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
A244
V
A
A
K
C
T
L
A
A
R
V
D
S
F
H
Dog
Lupus familis
XP_850917
499
55424
S263
R
K
T
L
S
G
F
S
S
T
S
V
L
P
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
S263
R
K
T
L
S
G
F
S
S
T
S
V
L
P
H
Rat
Rattus norvegicus
NP_001099689
499
55397
S263
R
K
T
L
S
G
F
S
S
T
S
V
L
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
N198
C
D
M
A
L
E
L
N
A
S
K
H
R
I
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
S262
R
K
T
L
T
G
F
S
S
T
S
V
L
P
H
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
S274
R
R
T
L
S
G
F
S
S
T
S
L
L
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
S271
K
K
T
L
S
G
F
S
Q
T
Q
M
L
P
H
Honey Bee
Apis mellifera
XP_394383
488
54294
S260
K
T
T
L
S
G
F
S
Q
V
A
T
L
P
H
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
S272
K
K
N
L
I
G
F
S
T
V
S
T
N
P
H
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
S261
R
K
M
L
S
G
F
S
S
S
A
V
L
P
H
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
S263
K
K
N
L
A
G
F
S
T
A
T
S
Q
F
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
T274
H
L
S
H
E
L
H
T
L
E
S
G
V
R
Q
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
K333
K
A
L
F
R
A
L
K
T
K
H
A
T
P
K
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
0
N.A.
93.3
86.6
N.A.
73.3
60
53.3
80
P-Site Similarity:
100
13.3
20
100
N.A.
100
100
N.A.
26.6
N.A.
100
100
N.A.
86.6
73.3
66.6
93.3
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
33.3
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
60
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
13
7
7
7
0
7
13
7
13
13
0
0
0
% A
% Cys:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% D
% Glu:
0
0
0
0
7
7
0
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
69
0
0
0
0
0
0
13
0
% F
% Gly:
0
0
0
0
0
69
0
0
0
0
0
7
0
0
0
% G
% His:
7
0
0
7
0
0
7
0
0
0
7
7
0
0
69
% H
% Ile:
0
0
0
0
13
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
32
57
0
7
0
0
0
7
0
7
7
0
0
0
7
% K
% Leu:
0
7
7
69
7
7
19
0
7
0
0
7
57
0
0
% L
% Met:
0
0
13
0
0
7
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
7
13
0
0
0
0
7
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
69
0
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
7
0
7
0
7
% Q
% Arg:
44
7
0
0
7
0
0
0
0
7
0
0
7
7
7
% R
% Ser:
0
0
7
0
50
0
0
69
50
13
50
7
13
0
0
% S
% Thr:
7
7
50
7
7
7
0
7
19
44
13
13
7
7
7
% T
% Val:
7
0
0
0
0
0
7
7
0
19
7
38
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _