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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
24.55
Human Site:
S282
Identified Species:
36
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
S282
Y
H
S
D
I
V
Q
S
L
P
P
D
L
R
R
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
R186
L
S
E
E
E
L
E
R
L
E
E
A
C
D
M
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
K263
G
K
V
G
Y
E
L
K
D
E
I
E
R
K
F
Dog
Lupus familis
XP_850917
499
55424
S282
Y
H
S
D
I
V
Q
S
L
P
P
D
L
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
S282
Y
H
S
D
I
V
Q
S
L
P
P
D
L
R
R
Rat
Rattus norvegicus
NP_001099689
499
55397
S282
Y
H
S
D
I
V
Q
S
L
P
P
D
L
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
P217
S
R
M
S
F
I
A
P
N
L
S
L
I
I
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
S281
Y
H
S
E
I
V
Q
S
L
P
S
D
L
H
R
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
T293
Y
H
C
D
V
V
Q
T
L
P
P
D
L
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
D290
Y
Y
S
Q
I
V
Q
D
T
A
P
D
L
R
R
Honey Bee
Apis mellifera
XP_394383
488
54294
E279
Y
Y
S
D
I
V
Q
E
T
P
P
D
L
R
R
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
K291
Y
F
H
Q
L
V
Q
K
M
P
P
D
L
K
N
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
A280
Y
Y
S
D
I
V
Q
A
T
P
Q
E
M
R
R
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
S282
E
Q
T
E
V
F
Q
S
T
P
P
S
L
R
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
K293
F
A
S
D
M
I
Q
K
F
P
V
S
V
H
K
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
Q352
Y
H
A
S
L
V
G
Q
A
S
G
A
N
K
G
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
6.6
0
100
N.A.
100
100
N.A.
0
N.A.
80
80
N.A.
66.6
80
46.6
60
P-Site Similarity:
100
26.6
13.3
100
N.A.
100
100
N.A.
13.3
N.A.
86.6
93.3
N.A.
73.3
86.6
66.6
86.6
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
40
N.A.
N.A.
N.A.
26.6
20
P-Site Similarity:
60
N.A.
N.A.
N.A.
60
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
7
7
7
7
0
13
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
50
0
0
0
7
7
0
0
57
0
7
0
% D
% Glu:
7
0
7
19
7
7
7
7
0
13
7
13
0
0
0
% E
% Phe:
7
7
0
0
7
7
0
0
7
0
0
0
0
0
7
% F
% Gly:
7
0
0
7
0
0
7
0
0
0
7
0
0
0
13
% G
% His:
0
44
7
0
0
0
0
0
0
0
0
0
0
13
0
% H
% Ile:
0
0
0
0
50
13
0
0
0
0
7
0
7
7
0
% I
% Lys:
0
7
0
0
0
0
0
19
0
0
0
0
0
19
7
% K
% Leu:
7
0
0
0
13
7
7
0
44
7
0
7
63
0
0
% L
% Met:
0
0
7
0
7
0
0
0
7
0
0
0
7
0
13
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
7
% N
% Pro:
0
0
0
0
0
0
0
7
0
69
57
0
0
0
0
% P
% Gln:
0
7
0
13
0
0
75
7
0
0
7
0
0
0
0
% Q
% Arg:
0
7
0
0
0
0
0
7
0
0
0
0
7
57
57
% R
% Ser:
7
7
57
13
0
0
0
38
0
7
13
13
0
0
0
% S
% Thr:
0
0
7
0
0
0
0
7
25
0
0
0
0
0
0
% T
% Val:
0
0
7
0
13
69
0
0
0
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
69
19
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _