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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
29.39
Human Site:
S307
Identified Species:
43.11
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
S307
T
L
A
A
R
V
D
S
F
H
E
S
T
E
G
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
V208
K
H
R
I
Y
E
Y
V
E
S
R
M
S
F
I
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
L285
P
V
K
Q
V
K
P
L
P
A
P
L
D
G
Q
Dog
Lupus familis
XP_850917
499
55424
S307
T
L
A
A
R
V
D
S
F
H
E
S
T
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
S307
T
L
A
A
R
V
D
S
F
H
E
S
T
E
G
Rat
Rattus norvegicus
NP_001099689
499
55397
S307
T
L
A
A
R
V
D
S
F
H
E
S
T
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
T239
M
G
V
A
G
G
L
T
N
L
S
K
M
P
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
S306
T
L
A
S
R
V
D
S
F
H
E
N
P
E
G
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
S318
T
L
A
S
R
V
D
S
F
H
E
S
A
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
A315
V
L
A
A
R
V
D
A
C
H
E
S
V
H
G
Honey Bee
Apis mellifera
XP_394383
488
54294
A304
M
L
A
A
R
V
D
A
C
H
E
S
T
D
G
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
A316
T
L
V
A
R
I
D
A
Q
H
E
S
S
N
G
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
S305
T
L
A
S
R
I
D
S
F
H
E
S
P
I
G
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
S307
T
L
A
A
R
V
D
S
T
R
G
D
P
S
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
A318
S
L
A
A
R
V
D
A
G
Q
K
N
G
D
R
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
D384
A
L
A
E
F
P
E
D
A
D
D
E
T
R
A
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
6.6
N.A.
80
80
N.A.
66.6
73.3
60
73.3
P-Site Similarity:
100
6.6
6.6
100
N.A.
100
100
N.A.
13.3
N.A.
93.3
93.3
N.A.
73.3
86.6
80
86.6
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
60
N.A.
N.A.
N.A.
40
20
P-Site Similarity:
60
N.A.
N.A.
N.A.
73.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
75
63
0
0
0
25
7
7
0
0
7
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
75
7
0
7
7
7
7
19
0
% D
% Glu:
0
0
0
7
0
7
7
0
7
0
63
7
0
32
0
% E
% Phe:
0
0
0
0
7
0
0
0
44
0
0
0
0
7
0
% F
% Gly:
0
7
0
0
7
7
0
0
7
0
7
0
7
7
69
% G
% His:
0
7
0
0
0
0
0
0
0
63
0
0
0
7
0
% H
% Ile:
0
0
0
7
0
13
0
0
0
0
0
0
0
7
7
% I
% Lys:
7
0
7
0
0
7
0
0
0
0
7
7
0
0
0
% K
% Leu:
0
82
0
0
0
0
7
7
0
7
0
7
0
0
0
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
13
0
7
0
% N
% Pro:
7
0
0
0
0
7
7
0
7
0
7
0
19
7
0
% P
% Gln:
0
0
0
7
0
0
0
0
7
7
0
0
0
0
7
% Q
% Arg:
0
0
7
0
75
0
0
0
0
7
7
0
0
7
7
% R
% Ser:
7
0
0
19
0
0
0
50
0
7
7
57
13
7
0
% S
% Thr:
57
0
0
0
0
0
0
7
7
0
0
0
38
0
0
% T
% Val:
7
7
13
0
7
63
0
7
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _