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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
34.55
Human Site:
S395
Identified Species:
50.67
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
S395
Y
Q
E
D
L
G
F
S
L
G
H
L
G
K
S
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
H270
S
S
T
S
V
L
P
H
T
G
Y
I
Y
H
S
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
G347
H
L
G
K
S
G
S
G
R
V
R
Q
T
Q
V
Dog
Lupus familis
XP_850917
499
55424
S395
Y
Q
E
D
L
G
F
S
L
G
H
L
G
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
S395
Y
Q
E
D
L
G
F
S
L
G
H
L
G
K
S
Rat
Rattus norvegicus
NP_001099689
499
55397
S395
Y
Q
E
D
L
G
F
S
L
G
H
L
G
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
E301
A
A
E
K
K
V
A
E
A
N
Q
K
Y
F
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
S394
Y
Q
E
D
L
G
F
S
L
G
H
L
G
K
S
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
S406
Y
Q
E
D
L
G
F
S
L
G
Q
L
G
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
S403
Y
Q
G
D
L
G
Y
S
R
G
T
I
G
K
T
Honey Bee
Apis mellifera
XP_394383
488
54294
S392
Y
Q
E
D
L
G
Y
S
R
G
T
I
G
K
A
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
D404
M
Q
E
H
M
G
F
D
I
G
Q
V
K
T
G
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
S393
Y
Q
E
D
L
G
F
S
L
G
Q
I
G
K
G
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
S386
Q
F
G
V
P
E
E
S
S
L
G
D
G
L
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
H383
K
E
K
F
R
L
S
H
V
R
Q
L
Q
N
R
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
K477
A
D
E
D
E
E
M
K
D
V
S
K
K
S
K
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
13.3
6.6
100
N.A.
100
100
N.A.
13.3
N.A.
100
93.3
N.A.
60
66.6
33.3
80
P-Site Similarity:
100
33.3
20
100
N.A.
100
100
N.A.
13.3
N.A.
100
93.3
N.A.
80
86.6
53.3
86.6
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
13.3
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
7
0
0
0
0
7
0
7
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
63
0
0
0
7
7
0
0
7
0
0
0
% D
% Glu:
0
7
69
0
7
13
7
7
0
0
0
0
0
0
0
% E
% Phe:
0
7
0
7
0
0
50
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
19
0
0
69
0
7
0
69
7
0
63
0
19
% G
% His:
7
0
0
7
0
0
0
13
0
0
32
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
25
0
0
0
% I
% Lys:
7
0
7
13
7
0
0
7
0
0
0
13
13
57
7
% K
% Leu:
0
7
0
0
57
13
0
0
44
7
0
44
0
7
0
% L
% Met:
7
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% N
% Pro:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
7
63
0
0
0
0
0
0
0
0
32
7
7
7
0
% Q
% Arg:
0
0
0
0
7
0
0
0
19
7
7
0
0
0
7
% R
% Ser:
7
7
0
7
7
0
13
63
7
0
7
0
0
7
50
% S
% Thr:
0
0
7
0
0
0
0
0
7
0
13
0
7
7
7
% T
% Val:
0
0
0
7
7
7
0
0
7
13
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
57
0
0
0
0
0
13
0
0
0
7
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _