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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
20.91
Human Site:
S44
Identified Species:
30.67
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
S44
E
E
T
Q
L
D
L
S
G
D
S
V
K
T
I
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
V34
E
A
A
P
E
Y
R
V
I
V
D
A
N
N
L
Dog
Lupus familis
XP_850917
499
55424
S44
E
E
T
Q
L
D
L
S
G
D
S
V
K
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
S44
E
E
T
Q
L
D
L
S
G
D
S
V
K
S
I
Rat
Rattus norvegicus
NP_001099689
499
55397
S44
E
E
T
Q
L
D
L
S
G
D
S
V
K
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
N43
E
E
M
Q
V
D
L
N
A
E
S
V
K
S
I
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
S55
E
M
E
V
D
Y
S
S
T
E
S
V
T
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
T52
N
L
M
D
V
D
V
T
V
Q
S
V
R
E
L
Honey Bee
Apis mellifera
XP_394383
488
54294
K41
K
T
I
E
E
E
I
K
V
A
S
V
R
E
L
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
K53
E
E
P
M
D
T
T
K
Y
A
S
V
H
D
V
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
T42
D
V
T
M
E
I
D
T
R
E
S
S
I
K
S
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
N46
L
A
D
I
E
A
L
N
Y
D
D
L
D
T
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
K40
T
V
N
C
Q
T
E
K
F
N
P
F
E
I
L
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
T114
I
Q
P
I
A
D
S
T
T
T
D
L
F
R
A
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
0
6.6
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
60
33.3
N.A.
20
13.3
26.6
13.3
P-Site Similarity:
100
0
13.3
100
N.A.
100
100
N.A.
0
N.A.
86.6
46.6
N.A.
53.3
53.3
33.3
33.3
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
20
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
40
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
7
0
7
7
0
0
7
13
0
7
0
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
7
13
44
7
0
0
32
19
0
7
7
0
% D
% Glu:
50
38
7
7
25
7
7
0
0
19
0
0
7
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
7
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
7
0
7
13
0
7
7
0
7
0
0
0
7
7
38
% I
% Lys:
7
0
0
0
0
0
0
19
0
0
0
0
32
7
0
% K
% Leu:
7
7
0
0
25
0
38
0
0
0
0
13
0
0
25
% L
% Met:
0
7
13
13
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
0
0
13
0
7
0
0
7
7
0
% N
% Pro:
0
0
13
7
0
0
0
0
0
0
7
0
0
0
0
% P
% Gln:
0
7
0
32
7
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
7
0
0
0
13
7
0
% R
% Ser:
0
0
0
0
0
0
13
32
0
0
63
7
0
32
7
% S
% Thr:
7
7
32
0
0
13
7
19
13
7
0
0
7
13
0
% T
% Val:
0
13
0
7
13
0
7
7
13
7
0
57
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
0
0
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _