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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
20.91
Human Site:
S481
Identified Species:
30.67
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
S481
E
A
N
Q
K
Y
F
S
S
M
A
E
F
L
K
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
W347
T
R
S
I
S
P
A
W
L
S
S
S
R
S
R
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
S424
A
N
Q
K
Y
F
S
S
M
A
E
F
L
K
V
Dog
Lupus familis
XP_850917
499
55424
S481
E
A
N
Q
K
Y
F
S
S
M
A
E
F
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
S481
E
A
N
Q
K
Y
F
S
S
M
A
E
F
L
K
Rat
Rattus norvegicus
NP_001099689
499
55397
S481
E
A
N
Q
K
Y
F
S
S
M
A
E
F
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
V378
L
K
K
V
S
E
G
V
E
Q
F
E
D
I
W
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
S480
E
A
N
Q
K
Y
F
S
S
M
A
E
F
L
K
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
E485
A
A
E
K
K
V
A
E
A
N
Q
K
Y
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
N483
E
R
S
Q
T
E
A
N
A
K
Y
F
S
N
T
Honey Bee
Apis mellifera
XP_394383
488
54294
E470
A
A
E
K
K
V
N
E
A
N
A
K
Y
F
S
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
S484
A
Q
E
Q
Q
Q
C
S
S
T
S
N
Y
F
S
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
A491
N
D
F
K
A
Q
E
A
N
D
R
Y
F
S
T
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
G466
H
A
H
Q
L
G
S
G
T
Q
S
T
Y
F
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
N467
G
H
N
T
E
Q
P
N
L
S
P
E
M
V
Q
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
A576
S
S
K
R
K
A
E
A
E
E
E
E
T
T
K
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
0
6.6
100
N.A.
100
100
N.A.
6.6
N.A.
100
13.3
N.A.
13.3
20
20
6.6
P-Site Similarity:
100
20
20
100
N.A.
100
100
N.A.
13.3
N.A.
100
40
N.A.
33.3
46.6
40
26.6
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
13.3
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
40
N.A.
N.A.
N.A.
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
50
0
0
7
7
19
13
19
7
38
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
7
0
0
7
0
0
% D
% Glu:
38
0
19
0
7
13
13
13
13
7
13
50
0
0
0
% E
% Phe:
0
0
7
0
0
7
32
0
0
0
7
13
38
25
0
% F
% Gly:
7
0
0
0
0
7
7
7
0
0
0
0
0
0
0
% G
% His:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
7
13
25
50
0
0
0
0
7
0
13
0
7
38
% K
% Leu:
7
0
0
0
7
0
0
0
13
0
0
0
7
32
0
% L
% Met:
0
0
0
0
0
0
0
0
7
32
0
0
7
0
0
% M
% Asn:
7
7
38
0
0
0
7
13
7
13
0
7
0
7
0
% N
% Pro:
0
0
0
0
0
7
7
0
0
0
7
0
0
0
0
% P
% Gln:
0
7
7
50
7
19
0
0
0
13
7
0
0
0
7
% Q
% Arg:
0
13
0
7
0
0
0
0
0
0
7
0
7
0
7
% R
% Ser:
7
7
13
0
13
0
13
44
38
13
19
7
7
13
25
% S
% Thr:
7
0
0
7
7
0
0
0
7
7
0
7
7
7
13
% T
% Val:
0
0
0
7
0
13
0
7
0
0
0
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
7
32
0
0
0
0
7
7
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _