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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
16.43
Human Site:
S494
Identified Species:
24.1
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
S494
L
K
V
K
G
E
K
S
G
L
M
S
T
_
_
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
Dog
Lupus familis
XP_850917
499
55424
S494
L
K
V
K
G
E
K
S
G
I
M
S
T
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
S494
L
K
V
K
G
E
K
S
G
T
M
S
T
_
_
Rat
Rattus norvegicus
NP_001099689
499
55397
S494
L
K
V
K
G
E
K
S
G
T
M
S
T
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
S493
L
K
V
K
S
E
K
S
G
T
M
T
Q
_
_
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
L498
F
S
N
M
A
E
F
L
K
V
K
R
E
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
V496
N
T
S
G
F
M
S
V
G
Q
R
T
T
_
_
Honey Bee
Apis mellifera
XP_394383
488
54294
L483
F
S
N
T
A
G
F
L
K
V
K
K
T
_
_
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
V497
F
S
S
S
G
S
F
V
N
I
D
R
M
T
L
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
K504
S
T
I
S
G
F
Q
K
V
K
D
D
A
G
V
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
H480
V
Q
M
H
K
K
Q
H
T
N
P
E
E
E
T
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
K589
T
K
E
E
K
P
K
K
K
K
K
K
S
S
K
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
0
0
92.3
N.A.
92.3
92.3
N.A.
0
N.A.
69.2
6.6
N.A.
15.3
7.6
6.6
6.6
P-Site Similarity:
100
0
0
100
N.A.
92.3
92.3
N.A.
0
N.A.
76.9
13.3
N.A.
23
15.3
13.3
26.6
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
0
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
0
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
13
7
0
0
0
% D
% Glu:
0
0
7
7
0
38
0
0
0
0
0
7
13
7
7
% E
% Phe:
19
0
0
0
7
7
19
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
38
7
0
0
38
0
0
0
0
7
0
% G
% His:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
0
38
0
32
13
7
38
13
19
13
19
13
0
7
7
% K
% Leu:
32
0
0
0
0
0
0
13
0
7
0
0
0
0
7
% L
% Met:
0
0
7
7
0
7
0
0
0
0
32
0
7
0
0
% M
% Asn:
7
0
13
0
0
0
0
0
7
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
13
0
0
7
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
13
0
0
0
% R
% Ser:
7
19
13
13
7
7
7
32
0
0
0
25
7
7
0
% S
% Thr:
7
13
0
7
0
0
0
0
7
19
0
13
38
7
7
% T
% Val:
7
0
32
0
0
0
0
13
7
13
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
44
44
% _