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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
23.03
Human Site:
S78
Identified Species:
33.78
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
S78
I
S
K
Q
A
K
A
S
E
V
M
G
P
V
E
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
E68
S
K
R
F
P
E
L
E
S
L
V
P
N
A
L
Dog
Lupus familis
XP_850917
499
55424
S78
I
S
K
Q
A
K
A
S
E
V
M
G
P
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
S78
I
S
K
Q
A
N
A
S
E
V
M
G
P
V
E
Rat
Rattus norvegicus
NP_001099689
499
55397
S78
I
S
K
Q
A
K
A
S
E
V
M
G
P
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
S22
A
E
E
E
E
G
G
S
Y
G
E
E
E
E
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
S77
I
Q
K
Q
P
K
A
S
E
V
M
G
P
V
E
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
S89
V
G
N
Q
R
K
N
S
E
V
S
G
P
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
A86
A
S
R
Q
R
T
A
A
E
M
L
G
S
V
E
Honey Bee
Apis mellifera
XP_394383
488
54294
A75
S
K
I
P
R
K
S
A
D
I
I
G
P
V
E
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
V87
L
K
R
P
Q
D
E
V
K
V
T
A
P
L
E
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
G76
Y
Q
D
N
P
R
K
G
E
V
M
G
P
V
E
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
Q80
L
E
K
G
S
G
V
Q
D
H
G
M
V
L
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
L74
L
S
E
T
A
Q
I
L
P
K
I
V
D
L
K
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
S148
M
S
L
G
L
S
H
S
L
S
R
H
K
L
K
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
0
0
100
N.A.
93.3
100
N.A.
13.3
N.A.
86.6
60
N.A.
46.6
33.3
20
46.6
P-Site Similarity:
100
0
26.6
100
N.A.
93.3
100
N.A.
26.6
N.A.
86.6
66.6
N.A.
73.3
66.6
46.6
53.3
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
13.3
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
40
N.A.
N.A.
N.A.
53.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
32
0
38
13
0
0
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
7
0
0
13
0
0
0
7
0
0
% D
% Glu:
0
13
13
7
7
7
7
7
50
0
7
7
7
7
75
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
13
0
13
7
7
0
7
7
57
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
7
0
7
0
0
0
% H
% Ile:
32
0
7
0
0
0
7
0
0
7
13
0
0
0
0
% I
% Lys:
0
19
38
0
0
38
7
0
7
7
0
0
7
0
13
% K
% Leu:
19
0
7
0
7
0
7
7
7
7
7
0
0
25
7
% L
% Met:
7
0
0
0
0
0
0
0
0
7
38
7
0
0
0
% M
% Asn:
0
0
7
7
0
7
7
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
13
19
0
0
0
7
0
0
7
57
0
0
% P
% Gln:
0
13
0
44
7
7
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
19
0
19
7
0
0
0
0
7
0
0
0
0
% R
% Ser:
13
44
0
0
7
7
7
50
7
7
7
0
7
0
0
% S
% Thr:
0
0
0
7
0
7
0
0
0
0
7
0
0
0
0
% T
% Val:
7
0
0
0
0
0
7
7
0
50
7
7
7
57
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _