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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
24.55
Human Site:
T427
Identified Species:
36
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
T427
I
S
K
T
L
Q
R
T
L
Q
K
Q
S
V
V
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
A302
V
A
A
K
C
T
L
A
A
R
V
D
S
F
H
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
G379
K
Q
S
V
V
Y
G
G
K
S
T
I
R
D
R
Dog
Lupus familis
XP_850917
499
55424
T427
I
S
K
T
L
Q
R
T
L
Q
K
Q
S
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
T427
I
S
K
T
L
Q
R
T
L
Q
K
Q
S
V
V
Rat
Rattus norvegicus
NP_001099689
499
55397
T427
I
S
K
T
L
Q
R
T
L
Q
K
Q
S
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
G333
G
F
S
L
G
H
L
G
K
S
G
S
G
R
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
T426
I
S
K
T
L
Q
R
T
L
Q
K
Q
S
V
V
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
T438
I
S
K
S
L
Q
R
T
L
Q
K
Q
S
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
N435
I
S
K
T
L
H
K
N
L
Q
K
Q
Q
V
Y
Honey Bee
Apis mellifera
XP_394383
488
54294
N424
I
S
K
T
L
Q
K
N
L
Q
K
Q
Q
Q
W
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
M436
A
R
M
S
Q
K
M
M
R
Q
M
E
R
Q
K
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
E425
I
S
K
S
L
Q
R
E
R
E
R
E
R
G
G
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
A418
I
G
Q
S
K
L
A
A
K
V
A
K
K
F
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
T415
V
G
L
G
M
S
N
T
S
L
Q
Q
A
V
G
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
R509
L
D
D
E
D
F
E
R
L
A
K
A
A
G
M
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
6.6
0
100
N.A.
100
100
N.A.
6.6
N.A.
100
80
N.A.
66.6
66.6
6.6
40
P-Site Similarity:
100
26.6
6.6
100
N.A.
100
100
N.A.
6.6
N.A.
100
93.3
N.A.
73.3
73.3
26.6
66.6
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
6.6
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
46.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
0
0
7
13
7
7
7
7
13
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
7
0
0
0
0
0
0
7
0
7
0
% D
% Glu:
0
0
0
7
0
0
7
7
0
7
0
13
0
0
0
% E
% Phe:
0
7
0
0
0
7
0
0
0
0
0
0
0
13
0
% F
% Gly:
7
13
0
7
7
0
7
13
0
0
7
0
7
13
13
% G
% His:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
7
% H
% Ile:
63
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
7
0
57
7
7
7
13
0
19
0
57
7
7
0
13
% K
% Leu:
7
0
7
7
57
7
13
0
57
7
0
0
0
0
0
% L
% Met:
0
0
7
0
7
0
7
7
0
0
7
0
0
7
7
% M
% Asn:
0
0
0
0
0
0
7
13
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
7
0
7
50
0
0
0
57
7
57
13
13
0
% Q
% Arg:
0
7
0
0
0
0
44
7
13
7
7
0
19
7
7
% R
% Ser:
0
57
13
25
0
7
0
0
7
13
0
7
44
0
0
% S
% Thr:
0
0
0
44
0
7
0
44
0
0
7
0
0
0
7
% T
% Val:
13
0
0
7
7
0
0
0
0
7
7
0
0
44
38
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _