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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
46.97
Human Site:
Y118
Identified Species:
68.89
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
Y118
H
K
F
I
R
D
K
Y
S
K
R
F
P
E
L
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
E28
G
S
Y
G
E
E
E
E
E
P
A
I
E
D
V
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
T105
Q
Q
I
L
T
N
A
T
I
M
V
V
S
V
T
Dog
Lupus familis
XP_850917
499
55424
Y118
H
K
F
I
R
D
K
Y
S
K
R
F
P
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
Y118
H
K
F
I
R
D
K
Y
S
K
R
F
P
E
L
Rat
Rattus norvegicus
NP_001099689
499
55397
Y118
H
K
F
I
R
D
K
Y
S
K
R
F
P
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
M59
A
K
L
W
D
S
K
M
F
A
E
I
M
V
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
Y117
H
K
F
I
R
D
K
Y
S
K
R
F
P
E
L
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
Y129
H
K
F
V
R
D
K
Y
S
K
R
F
P
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
Y126
H
K
F
T
K
E
K
Y
Q
K
R
F
P
E
L
Honey Bee
Apis mellifera
XP_394383
488
54294
Y115
H
R
F
T
R
D
K
Y
S
K
R
F
P
E
L
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
Y127
H
K
F
V
R
D
K
Y
E
K
R
F
P
E
L
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
Y116
H
K
F
V
R
D
H
Y
Q
K
R
F
P
E
L
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
Y120
H
N
F
I
R
D
K
Y
R
L
K
F
P
E
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
Y120
H
N
F
L
I
S
L
Y
S
R
R
F
P
E
L
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
E188
T
Y
A
M
R
V
K
E
W
Y
G
W
H
F
P
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
13.3
N.A.
100
93.3
N.A.
73.3
86.6
86.6
80
P-Site Similarity:
100
33.3
20
100
N.A.
100
100
N.A.
13.3
N.A.
100
100
N.A.
86.6
93.3
93.3
86.6
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
73.3
N.A.
N.A.
N.A.
60
13.3
P-Site Similarity:
80
N.A.
N.A.
N.A.
73.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
7
0
0
7
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
63
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
7
13
7
13
13
0
7
0
7
75
0
% E
% Phe:
0
0
75
0
0
0
0
0
7
0
0
75
0
7
0
% F
% Gly:
7
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
75
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
7
38
7
0
0
0
7
0
0
13
0
0
0
% I
% Lys:
0
63
0
0
7
0
75
0
0
63
7
0
0
0
7
% K
% Leu:
0
0
7
13
0
0
7
0
0
7
0
0
0
0
75
% L
% Met:
0
0
0
7
0
0
0
7
0
7
0
0
7
0
0
% M
% Asn:
0
13
0
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
0
75
0
7
% P
% Gln:
7
7
0
0
0
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
69
0
0
0
7
7
69
0
0
0
0
% R
% Ser:
0
7
0
0
0
13
0
0
50
0
0
0
7
0
0
% S
% Thr:
7
0
0
13
7
0
0
7
0
0
0
0
0
0
7
% T
% Val:
0
0
0
19
0
7
0
0
0
0
7
7
0
13
7
% V
% Trp:
0
0
0
7
0
0
0
0
7
0
0
7
0
0
0
% W
% Tyr:
0
7
7
0
0
0
0
75
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _