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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
29.09
Human Site:
Y205
Identified Species:
42.67
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
Y205
N
A
S
K
H
R
I
Y
E
Y
V
E
S
R
M
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
I110
I
E
N
E
L
N
I
I
H
K
F
I
R
D
K
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
P187
L
T
N
L
S
K
M
P
A
C
N
I
M
L
L
Dog
Lupus familis
XP_850917
499
55424
Y205
N
A
S
K
H
R
I
Y
E
Y
V
E
S
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
Y205
N
A
S
K
H
R
I
Y
E
Y
V
E
S
R
M
Rat
Rattus norvegicus
NP_001099689
499
55397
Y205
N
A
S
K
H
R
I
Y
E
Y
V
E
S
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
E141
D
Y
I
R
T
V
K
E
L
G
N
S
L
D
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
Y204
N
Q
S
K
H
R
I
Y
E
Y
V
E
S
R
M
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
Y216
N
Q
S
K
H
R
I
Y
E
Y
V
E
S
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
Y213
N
N
F
K
S
K
I
Y
E
Y
V
E
S
R
M
Honey Bee
Apis mellifera
XP_394383
488
54294
F202
N
N
C
K
L
K
I
F
E
Y
V
E
S
R
M
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
H214
H
V
N
R
L
E
M
H
Q
L
V
E
W
R
M
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
F203
K
Q
A
K
T
D
I
F
T
Y
V
E
S
R
M
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
L205
D
S
A
K
K
K
V
L
D
F
V
E
T
R
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
G215
W
K
L
Q
E
D
I
G
Q
Y
I
A
S
K
I
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
S275
S
V
Y
R
K
Q
L
S
D
Y
L
E
N
R
M
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
6.6
0
100
N.A.
100
100
N.A.
0
N.A.
93.3
93.3
N.A.
73.3
66.6
26.6
53.3
P-Site Similarity:
100
20
26.6
100
N.A.
100
100
N.A.
13.3
N.A.
93.3
93.3
N.A.
80
80
66.6
66.6
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
33.3
N.A.
N.A.
N.A.
20
26.6
P-Site Similarity:
86.6
N.A.
N.A.
N.A.
53.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
13
0
0
0
0
0
7
0
0
7
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
13
0
0
13
0
0
0
0
13
0
% D
% Glu:
0
7
0
7
7
7
0
7
50
0
0
75
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
13
0
7
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% G
% His:
7
0
0
0
38
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
7
0
7
0
0
0
69
7
0
0
7
13
0
0
7
% I
% Lys:
7
7
0
63
13
25
7
0
0
7
0
0
0
7
13
% K
% Leu:
7
0
7
7
19
0
7
7
7
7
7
0
7
7
7
% L
% Met:
0
0
0
0
0
0
13
0
0
0
0
0
7
0
75
% M
% Asn:
50
13
19
0
0
7
0
0
0
0
13
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
19
0
7
0
7
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
0
0
19
0
38
0
0
0
0
0
0
7
75
0
% R
% Ser:
7
7
38
0
13
0
0
7
0
0
0
7
63
0
0
% S
% Thr:
0
7
0
0
13
0
0
0
7
0
0
0
7
0
0
% T
% Val:
0
13
0
0
0
7
7
0
0
0
69
0
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
7
7
0
0
0
0
44
0
69
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _