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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
40
Human Site:
Y207
Identified Species:
58.67
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
Y207
S
K
H
R
I
Y
E
Y
V
E
S
R
M
S
F
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
K112
N
E
L
N
I
I
H
K
F
I
R
D
K
Y
S
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
C189
N
L
S
K
M
P
A
C
N
I
M
L
L
G
A
Dog
Lupus familis
XP_850917
499
55424
Y207
S
K
H
R
I
Y
E
Y
V
E
S
R
M
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
Y207
S
K
H
R
I
Y
E
Y
V
E
S
R
M
S
F
Rat
Rattus norvegicus
NP_001099689
499
55397
Y207
S
K
H
R
I
Y
E
Y
V
E
S
R
M
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
G143
I
R
T
V
K
E
L
G
N
S
L
D
K
C
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
Y206
S
K
H
R
I
Y
E
Y
V
E
S
R
M
S
F
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
Y218
S
K
H
R
I
Y
E
Y
V
E
S
R
M
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
Y215
F
K
S
K
I
Y
E
Y
V
E
S
R
M
T
F
Honey Bee
Apis mellifera
XP_394383
488
54294
Y204
C
K
L
K
I
F
E
Y
V
E
S
R
M
A
F
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
L216
N
R
L
E
M
H
Q
L
V
E
W
R
M
A
L
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
Y205
A
K
T
D
I
F
T
Y
V
E
S
R
M
S
F
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
F207
A
K
K
K
V
L
D
F
V
E
T
R
M
G
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
Y217
L
Q
E
D
I
G
Q
Y
I
A
S
K
I
S
I
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
Y277
Y
R
K
Q
L
S
D
Y
L
E
N
R
M
R
A
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
6.6
0
100
N.A.
100
100
N.A.
0
N.A.
100
100
N.A.
73.3
66.6
26.6
66.6
P-Site Similarity:
100
20
26.6
100
N.A.
100
100
N.A.
6.6
N.A.
100
100
N.A.
86.6
86.6
66.6
80
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
33.3
N.A.
N.A.
N.A.
26.6
26.6
P-Site Similarity:
80
N.A.
N.A.
N.A.
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
7
0
0
7
0
0
0
13
13
% A
% Cys:
7
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% C
% Asp:
0
0
0
13
0
0
13
0
0
0
0
13
0
0
0
% D
% Glu:
0
7
7
7
0
7
50
0
0
75
0
0
0
0
0
% E
% Phe:
7
0
0
0
0
13
0
7
7
0
0
0
0
0
57
% F
% Gly:
0
0
0
0
0
7
0
7
0
0
0
0
0
13
0
% G
% His:
0
0
38
0
0
7
7
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
69
7
0
0
7
13
0
0
7
0
7
% I
% Lys:
0
63
13
25
7
0
0
7
0
0
0
7
13
0
7
% K
% Leu:
7
7
19
0
7
7
7
7
7
0
7
7
7
0
7
% L
% Met:
0
0
0
0
13
0
0
0
0
0
7
0
75
0
0
% M
% Asn:
19
0
0
7
0
0
0
0
13
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
7
0
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
0
19
0
38
0
0
0
0
0
0
7
75
0
7
0
% R
% Ser:
38
0
13
0
0
7
0
0
0
7
63
0
0
50
7
% S
% Thr:
0
0
13
0
0
0
7
0
0
0
7
0
0
7
0
% T
% Val:
0
0
0
7
7
0
0
0
69
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
7
0
0
0
0
44
0
69
0
0
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _