KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
14.85
Human Site:
Y23
Identified Species:
21.78
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
Y23
E
E
E
E
G
G
S
Y
G
E
E
E
E
E
P
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
S14
M
K
I
E
E
Y
I
S
K
Q
A
K
A
S
E
Dog
Lupus familis
XP_850917
499
55424
Y23
E
E
E
E
G
G
S
Y
G
E
E
E
E
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
Y23
E
E
E
E
G
G
S
Y
G
E
E
E
E
E
P
Rat
Rattus norvegicus
NP_001099689
499
55397
Y23
E
E
E
E
G
G
S
Y
G
E
E
E
E
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
I23
E
E
E
E
E
N
L
I
D
E
D
D
L
E
T
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
P22
G
E
E
D
G
L
Y
P
G
G
E
E
G
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
E18
L
E
E
D
N
D
N
E
L
E
E
E
D
S
E
Honey Bee
Apis mellifera
XP_394383
488
54294
I19
E
E
N
D
S
D
R
I
A
E
E
P
E
P
D
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
G31
D
L
G
E
N
L
K
G
V
K
K
E
E
L
D
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
D22
A
E
E
G
F
I
D
D
A
E
N
E
K
D
E
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
N20
E
L
S
D
N
D
A
N
I
E
E
D
D
V
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
V19
E
Y
D
L
A
D
E
V
N
E
E
K
E
D
I
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
V90
E
K
K
V
T
L
A
V
A
E
S
K
L
G
A
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
0
6.6
100
N.A.
100
100
N.A.
0
N.A.
40
46.6
N.A.
33.3
33.3
20
26.6
P-Site Similarity:
100
0
26.6
100
N.A.
100
100
N.A.
0
N.A.
53.3
53.3
N.A.
53.3
40
40
40
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
20
N.A.
N.A.
N.A.
26.6
13.3
P-Site Similarity:
46.6
N.A.
N.A.
N.A.
46.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
13
0
19
0
7
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
25
0
25
7
7
7
0
7
13
13
13
13
% D
% Glu:
57
57
50
44
13
0
7
7
0
69
57
50
44
38
25
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
7
32
25
0
7
32
7
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
7
7
13
7
0
0
0
0
0
7
% I
% Lys:
0
13
7
0
0
0
7
0
7
7
7
19
7
0
0
% K
% Leu:
7
13
0
7
0
19
7
0
7
0
0
0
13
7
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
19
7
7
7
7
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
7
0
7
25
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
0
7
0
25
7
0
0
7
0
0
13
7
% S
% Thr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% T
% Val:
0
0
0
7
0
0
0
13
7
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
7
7
25
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _