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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
40.91
Human Site:
Y275
Identified Species:
60
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
Y275
L
P
H
T
G
Y
I
Y
H
S
D
I
V
Q
S
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
L179
S
T
T
Q
G
Q
Q
L
S
E
E
E
L
E
R
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
G256
S
F
H
E
S
T
E
G
K
V
G
Y
E
L
K
Dog
Lupus familis
XP_850917
499
55424
Y275
L
P
H
T
G
Y
I
Y
H
S
D
I
V
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
Y275
L
P
H
T
G
Y
I
Y
H
S
D
I
V
Q
S
Rat
Rattus norvegicus
NP_001099689
499
55397
Y275
L
P
H
T
G
Y
I
Y
H
S
D
I
V
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
S210
R
I
Y
E
Y
V
E
S
R
M
S
F
I
A
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
Y274
L
P
H
T
G
Y
I
Y
H
S
E
I
V
Q
S
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
Y286
L
P
H
T
G
Y
I
Y
H
C
D
V
V
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
Y283
L
P
H
T
G
Y
V
Y
Y
S
Q
I
V
Q
D
Honey Bee
Apis mellifera
XP_394383
488
54294
Y272
L
P
H
T
G
F
I
Y
Y
S
D
I
V
Q
E
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
Y284
N
P
H
H
G
F
I
Y
F
H
Q
L
V
Q
K
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
Y273
L
P
H
T
G
Y
I
Y
Y
S
D
I
V
Q
A
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
E275
Q
F
R
V
G
F
I
E
Q
T
E
V
F
Q
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
F286
V
R
Q
E
G
Y
L
F
A
S
D
M
I
Q
K
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
Y345
T
P
K
Y
G
L
I
Y
H
A
S
L
V
G
Q
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
0
N.A.
93.3
80
N.A.
73.3
80
46.6
86.6
P-Site Similarity:
100
26.6
6.6
100
N.A.
100
100
N.A.
13.3
N.A.
100
93.3
N.A.
86.6
93.3
60
100
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
26.6
N.A.
N.A.
N.A.
33.3
40
P-Site Similarity:
53.3
N.A.
N.A.
N.A.
66.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
7
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
7
% D
% Glu:
0
0
0
19
0
0
13
7
0
7
19
7
7
7
7
% E
% Phe:
0
13
0
0
0
19
0
7
7
0
0
7
7
0
0
% F
% Gly:
0
0
0
0
88
0
0
7
0
0
7
0
0
7
0
% G
% His:
0
0
69
7
0
0
0
0
44
7
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
69
0
0
0
0
50
13
0
0
% I
% Lys:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
19
% K
% Leu:
57
0
0
0
0
7
7
7
0
0
0
13
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
69
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
7
0
7
7
0
7
7
0
7
0
13
0
0
75
7
% Q
% Arg:
7
7
7
0
0
0
0
0
7
0
0
0
0
0
7
% R
% Ser:
13
0
0
0
7
0
0
7
7
57
13
0
0
0
38
% S
% Thr:
7
7
7
57
0
7
0
0
0
7
0
0
0
0
7
% T
% Val:
7
0
0
7
0
7
7
0
0
7
0
13
69
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
7
57
0
69
19
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _