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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
22.12
Human Site:
Y318
Identified Species:
32.44
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
Y318
S
T
E
G
K
V
G
Y
E
L
K
D
E
I
E
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
L219
M
S
F
I
A
P
N
L
S
I
I
I
G
A
S
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
R296
L
D
G
Q
R
K
K
R
G
G
R
R
Y
R
K
Dog
Lupus familis
XP_850917
499
55424
Y318
S
T
E
G
K
V
G
Y
E
L
K
D
E
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
Y318
S
T
E
G
K
V
G
Y
E
L
K
D
E
I
E
Rat
Rattus norvegicus
NP_001099689
499
55397
Y318
S
T
E
G
K
V
G
Y
E
L
K
D
E
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
M250
K
M
P
A
C
N
I
M
L
L
G
A
Q
R
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
Y317
N
P
E
G
K
I
G
Y
D
L
K
E
E
I
E
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
Y329
S
A
D
G
K
V
G
Y
D
L
K
E
E
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
L326
S
V
H
G
E
I
G
L
R
F
K
E
D
V
E
Honey Bee
Apis mellifera
XP_394383
488
54294
Q315
S
T
D
G
H
I
G
Q
M
F
R
E
E
I
E
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
A327
S
S
N
G
E
K
G
A
E
F
L
A
L
V
E
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
L316
S
P
I
G
T
M
G
L
N
L
R
A
E
I
E
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
R318
D
P
S
G
N
T
G
R
A
L
R
E
E
I
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
L329
N
G
D
R
N
T
V
L
A
H
K
W
K
A
E
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
I395
E
T
R
A
S
L
G
I
R
S
R
A
K
L
E
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
6.6
N.A.
66.6
73.3
N.A.
33.3
46.6
33.3
46.6
P-Site Similarity:
100
13.3
20
100
N.A.
100
100
N.A.
20
N.A.
93.3
93.3
N.A.
66.6
73.3
53.3
60
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
33.3
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
46.6
N.A.
N.A.
N.A.
33.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
13
7
0
0
7
13
0
0
25
0
13
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
19
0
0
0
0
0
13
0
0
25
7
0
0
% D
% Glu:
7
0
32
0
13
0
0
0
32
0
0
32
57
0
75
% E
% Phe:
0
0
7
0
0
0
0
0
0
19
0
0
0
0
0
% F
% Gly:
0
7
7
69
0
0
75
0
7
7
7
0
7
0
0
% G
% His:
0
0
7
0
7
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
7
7
0
19
7
7
0
7
7
7
0
57
0
% I
% Lys:
7
0
0
0
38
13
7
0
0
0
50
0
13
0
13
% K
% Leu:
7
0
0
0
0
7
0
25
7
57
7
0
7
7
0
% L
% Met:
7
7
0
0
0
7
0
7
7
0
0
0
0
0
0
% M
% Asn:
13
0
7
0
13
7
7
0
7
0
0
0
0
0
0
% N
% Pro:
0
19
7
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
7
0
0
0
0
7
0
0
% Q
% Arg:
0
0
7
7
7
0
0
13
13
0
32
7
0
13
7
% R
% Ser:
57
13
7
0
7
0
0
0
7
7
0
0
0
0
7
% S
% Thr:
0
38
0
0
7
13
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
0
0
32
7
0
0
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
38
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _