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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF31
All Species:
35.45
Human Site:
Y388
Identified Species:
52
UniProt:
Q8WWY3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY3
NP_056444.3
499
55456
Y388
G
E
I
E
E
D
A
Y
Q
E
D
L
G
F
S
Chimpanzee
Pan troglodytes
XP_001174758
364
40747
S263
R
K
T
L
S
G
F
S
S
T
S
V
L
P
H
Rhesus Macaque
Macaca mulatta
XP_001116111
441
49083
H340
D
L
G
F
S
L
G
H
L
G
K
S
G
S
G
Dog
Lupus familis
XP_850917
499
55424
Y388
G
E
I
E
E
D
A
Y
Q
E
D
L
G
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCF0
499
55383
Y388
G
E
I
E
E
D
A
Y
Q
E
D
L
G
F
S
Rat
Rattus norvegicus
NP_001099689
499
55397
Y388
G
E
I
E
E
D
A
Y
Q
E
D
L
G
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519734
395
43621
A294
L
E
I
V
N
P
Q
A
A
E
K
K
V
A
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U5C5
498
55545
Y387
G
E
I
E
E
D
A
Y
Q
E
D
L
G
F
S
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
Y399
A
E
I
E
D
D
A
Y
Q
E
D
L
G
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648756
501
55526
Y396
G
D
I
E
E
D
A
Y
Q
G
D
L
G
Y
S
Honey Bee
Apis mellifera
XP_394383
488
54294
Y385
A
D
I
E
N
D
A
Y
Q
E
D
L
G
Y
S
Nematode Worm
Caenorhab. elegans
NP_491527
504
55599
M397
G
E
L
G
E
D
V
M
Q
E
H
M
G
F
D
Sea Urchin
Strong. purpuratus
XP_793603
512
56872
Y386
A
E
I
E
E
D
A
Y
Q
E
D
L
G
F
S
Poplar Tree
Populus trichocarpa
XP_002320218
483
52609
Q379
R
K
L
A
N
R
M
Q
F
G
V
P
E
E
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P49704
494
56284
K376
G
R
K
F
R
K
Y
K
E
K
F
R
L
S
H
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
A470
V
E
M
Q
D
A
P
A
D
E
D
E
E
M
K
Conservation
Percent
Protein Identity:
100
70.7
88.3
99.5
N.A.
99.1
99.4
N.A.
69.9
N.A.
89.3
82.2
N.A.
61.2
64.1
45.6
62.1
Protein Similarity:
100
71.5
88.3
100
N.A.
99.5
99.8
N.A.
74.1
N.A.
95.3
89.5
N.A.
78
78.3
68
78.7
P-Site Identity:
100
0
6.6
100
N.A.
100
100
N.A.
20
N.A.
100
86.6
N.A.
80
73.3
53.3
93.3
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
100
N.A.
20
N.A.
100
93.3
N.A.
93.3
86.6
66.6
93.3
Percent
Protein Identity:
44.6
N.A.
N.A.
N.A.
25.4
21.7
Protein Similarity:
65.1
N.A.
N.A.
N.A.
50.5
41.7
P-Site Identity:
6.6
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
20
N.A.
N.A.
N.A.
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
7
0
7
57
13
7
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
13
0
0
13
63
0
0
7
0
63
0
0
0
7
% D
% Glu:
0
63
0
57
50
0
0
0
7
69
0
7
13
7
7
% E
% Phe:
0
0
0
13
0
0
7
0
7
0
7
0
0
50
0
% F
% Gly:
50
0
7
7
0
7
7
0
0
19
0
0
69
0
7
% G
% His:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
13
% H
% Ile:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
13
7
0
0
7
0
7
0
7
13
7
0
0
7
% K
% Leu:
7
7
13
7
0
7
0
0
7
0
0
57
13
0
0
% L
% Met:
0
0
7
0
0
0
7
7
0
0
0
7
0
7
0
% M
% Asn:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
7
0
0
0
0
7
0
7
0
% P
% Gln:
0
0
0
7
0
0
7
7
63
0
0
0
0
0
0
% Q
% Arg:
13
7
0
0
7
7
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
0
0
0
13
0
0
7
7
0
7
7
0
13
63
% S
% Thr:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% T
% Val:
7
0
0
7
0
0
7
0
0
0
7
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
57
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _