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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WFDC12
All Species:
8.44
Human Site:
S105
Identified Species:
26.53
UniProt:
Q8WWY7
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY7
NP_543145.1
111
12050
S105
A
K
C
P
G
S
S
S
T
R
C
P
Q
K
_
Chimpanzee
Pan troglodytes
A4K2P0
111
12091
S105
A
K
C
P
G
S
S
S
T
R
C
P
Q
K
_
Rhesus Macaque
Macaca mulatta
A4K2T3
111
11642
S105
A
K
S
P
G
S
S
S
T
G
C
P
Q
K
_
Dog
Lupus familis
XP_534433
107
11019
K93
T
E
C
P
G
A
R
K
C
C
K
G
P
C
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHY3
85
9540
Rat
Rattus norvegicus
Q6IE40
78
8646
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509940
170
18421
I132
G
R
C
P
V
V
N
I
R
C
A
M
L
N
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084488
167
18504
A151
A
R
N
E
D
C
L
A
P
Q
K
C
C
Q
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
91.8
26.1
N.A.
40.5
45
N.A.
27.6
N.A.
23.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.1
93.6
35.1
N.A.
52.2
50.4
N.A.
38.2
N.A.
33.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
85.7
20
N.A.
0
0
N.A.
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
85.7
40
N.A.
0
0
N.A.
26.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
0
13
0
13
0
0
13
0
0
0
0
% A
% Cys:
0
0
50
0
0
13
0
0
13
25
38
13
13
13
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
13
0
13
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
50
0
0
0
0
13
0
13
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% I
% Lys:
0
38
0
0
0
0
0
13
0
0
25
0
0
38
0
% K
% Leu:
0
0
0
0
0
0
13
0
0
0
0
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% M
% Asn:
0
0
13
0
0
0
13
0
0
0
0
0
0
13
0
% N
% Pro:
0
0
0
63
0
0
0
0
13
0
0
38
13
0
13
% P
% Gln:
0
0
0
0
0
0
0
0
0
13
0
0
38
13
0
% Q
% Arg:
0
25
0
0
0
0
13
0
13
25
0
0
0
0
0
% R
% Ser:
0
0
13
0
0
38
38
38
0
0
0
0
0
0
13
% S
% Thr:
13
0
0
0
0
0
0
0
38
0
0
0
0
0
0
% T
% Val:
0
0
0
0
13
13
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
38
% _