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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIPH
All Species:
27.88
Human Site:
S400
Identified Species:
68.15
UniProt:
Q8WWY8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWY8
NP_640341.1
451
50859
S400
S
L
M
F
S
T
G
S
L
I
G
P
R
Y
K
Chimpanzee
Pan troglodytes
XP_516924
441
49574
S390
S
L
M
F
S
T
G
S
L
I
G
P
R
Y
K
Rhesus Macaque
Macaca mulatta
XP_001090044
479
54102
S428
S
L
M
F
S
T
G
S
I
I
G
P
R
Y
K
Dog
Lupus familis
XP_545236
467
52648
S416
S
L
V
F
S
T
G
S
V
I
G
P
K
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIV3
451
50657
S400
S
L
L
F
S
T
G
S
V
V
G
P
K
Y
K
Rat
Rattus norvegicus
Q32PY2
451
50807
S400
S
L
L
F
S
T
K
S
V
V
G
P
K
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512456
495
55836
Q445
K
I
S
M
T
Y
F
Q
K
G
G
S
S
C
I
Chicken
Gallus gallus
P11602
490
55114
S418
K
D
T
F
F
S
W
S
D
W
W
T
P
F
A
Frog
Xenopus laevis
Q6PA23
460
52044
S409
S
V
T
F
T
T
G
S
I
I
G
P
K
Y
K
Zebra Danio
Brachydanio rerio
Q6DBU8
454
51793
R407
F
C
P
R
K
G
L
R
P
R
K
K
L
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
80.7
81.1
N.A.
77.8
78.9
N.A.
42.6
28.7
61.5
48.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
86.8
90.3
N.A.
90.6
90.9
N.A.
56.9
44.4
78.9
67.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
73.3
66.6
N.A.
6.6
13.3
66.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
20
26.6
93.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
80
10
0
10
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
10
60
0
0
10
80
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
20
50
0
0
0
0
10
% I
% Lys:
20
0
0
0
10
0
10
0
10
0
10
10
40
0
70
% K
% Leu:
0
60
20
0
0
0
10
0
20
0
0
0
10
0
10
% L
% Met:
0
0
30
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
10
0
0
70
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
10
0
10
0
0
30
10
0
% R
% Ser:
70
0
10
0
60
10
0
80
0
0
0
10
10
0
0
% S
% Thr:
0
0
20
0
20
70
0
0
0
0
0
10
0
0
0
% T
% Val:
0
10
10
0
0
0
0
0
30
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
10
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _