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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPH All Species: 27.27
Human Site: Y373 Identified Species: 66.67
UniProt: Q8WWY8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WWY8 NP_640341.1 451 50859 Y373 E P T T F Q K Y H Q V S L L A
Chimpanzee Pan troglodytes XP_516924 441 49574 Y363 E P T A F Q K Y H Q V S L L A
Rhesus Macaque Macaca mulatta XP_001090044 479 54102 Y401 E P T T F Q K Y H Q V S L L A
Dog Lupus familis XP_545236 467 52648 Y389 E P A I F Q K Y H Q V S L L A
Cat Felis silvestris
Mouse Mus musculus Q8CIV3 451 50657 Y373 E P S A F E K Y H Q V S L L A
Rat Rattus norvegicus Q32PY2 451 50807 Y373 E P S A F Q K Y H Q V S L L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512456 495 55836 S411 T N K D P F C S D D Y V T L E
Chicken Gallus gallus P11602 490 55114 S385 F T L P E V S S N K T F S F L
Frog Xenopus laevis Q6PA23 460 52044 Y382 D H A T F Q Q Y K E T S L L A
Zebra Danio Brachydanio rerio Q6DBU8 454 51793 T380 K F E R F Q E T S V L A Q F E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 80.7 81.1 N.A. 77.8 78.9 N.A. 42.6 28.7 61.5 48.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.3 86.8 90.3 N.A. 90.6 90.9 N.A. 56.9 44.4 78.9 67.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 86.6 N.A. 80 86.6 N.A. 6.6 0 53.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 86.6 N.A. 93.3 93.3 N.A. 6.6 13.3 73.3 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 30 0 0 0 0 0 0 0 10 0 0 70 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 0 0 0 0 10 10 0 0 0 0 0 % D
% Glu: 60 0 10 0 10 10 10 0 0 10 0 0 0 0 20 % E
% Phe: 10 10 0 0 80 10 0 0 0 0 0 10 0 20 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 60 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 10 0 0 0 60 0 10 10 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 0 0 0 0 10 0 70 80 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 60 0 10 10 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 70 10 0 0 60 0 0 10 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 20 0 0 0 10 20 10 0 0 70 10 0 0 % S
% Thr: 10 10 30 30 0 0 0 10 0 0 20 0 10 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 10 60 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 70 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _