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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDARADD
All Species:
16.67
Human Site:
T49
Identified Species:
61.11
UniProt:
Q8WWZ3
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWZ3
NP_542776.1
215
24802
T49
D
K
Y
P
I
Q
D
T
E
L
P
K
A
E
E
Chimpanzee
Pan troglodytes
XP_514291
212
24456
T49
D
K
Y
P
I
Q
D
T
E
L
P
K
A
E
E
Rhesus Macaque
Macaca mulatta
XP_001099801
215
24664
T49
D
K
Y
P
V
Q
D
T
E
L
P
K
A
E
E
Dog
Lupus familis
XP_849101
271
30492
T105
D
K
Y
P
I
Q
D
T
E
L
P
K
A
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHX2
208
23735
C47
G
L
P
K
A
K
E
C
D
T
V
N
S
N
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012405
213
24477
Y47
G
V
P
K
D
E
E
Y
K
T
D
Q
V
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695138
295
34239
S128
Y
P
V
Q
V
T
D
S
Q
D
P
V
T
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
96.2
68.2
N.A.
74.8
N.A.
N.A.
N.A.
57.6
N.A.
33.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.7
98.1
73.4
N.A.
80
N.A.
N.A.
N.A.
69.7
N.A.
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
0
N.A.
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
N.A.
N.A.
N.A.
26.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
0
0
0
0
0
0
0
58
0
0
% A
% Cys:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
15
% C
% Asp:
58
0
0
0
15
0
72
0
15
15
15
0
0
0
15
% D
% Glu:
0
0
0
0
0
15
29
0
58
0
0
0
0
58
43
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
43
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
58
0
29
0
15
0
0
15
0
0
58
0
0
0
% K
% Leu:
0
15
0
0
0
0
0
0
0
58
0
0
0
15
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
15
0
15
0
% N
% Pro:
0
15
29
58
0
0
0
0
0
0
72
0
0
0
0
% P
% Gln:
0
0
0
15
0
58
0
0
15
0
0
15
0
0
15
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
15
0
0
0
0
15
0
0
% S
% Thr:
0
0
0
0
0
15
0
58
0
29
0
0
15
15
0
% T
% Val:
0
15
15
0
29
0
0
0
0
0
15
15
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
58
0
0
0
0
15
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _