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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA10
All Species:
3.64
Human Site:
S374
Identified Species:
8.89
UniProt:
Q8WWZ4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWZ4
NP_525021.3
1543
175746
S374
E
I
N
P
E
H
S
S
D
D
S
F
E
P
V
Chimpanzee
Pan troglodytes
XP_001165871
1606
181884
F445
E
M
D
A
D
P
S
F
H
D
S
F
E
R
V
Rhesus Macaque
Macaca mulatta
XP_001082622
1598
181015
S438
E
M
D
A
D
P
S
S
H
D
S
F
E
P
V
Dog
Lupus familis
XP_853718
1625
184408
P464
E
I
D
S
D
S
S
P
N
D
S
F
E
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K449
1623
183126
L464
E
I
D
S
D
P
S
L
N
D
S
L
E
P
V
Rat
Rattus norvegicus
Q8CF82
1642
185792
L461
N
I
N
G
N
I
S
L
N
E
I
V
E
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509469
1722
195635
F541
N
V
N
G
S
I
S
F
S
E
I
I
E
P
V
Chicken
Gallus gallus
XP_415691
1546
175373
P404
G
A
G
S
P
E
E
P
P
G
D
N
V
E
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
N481
E
A
P
E
D
D
E
N
Q
T
D
G
V
T
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
D519
E
T
D
M
F
P
A
D
I
E
V
N
Q
G
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.9
60.3
60
N.A.
57.4
40.9
N.A.
39.4
47.7
N.A.
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
100
74.9
75.7
74.6
N.A.
72.6
60.1
N.A.
58.4
66.3
N.A.
N.A.
N.A.
N.A.
N.A.
42.9
N.A.
P-Site Identity:
100
46.6
60
60
N.A.
53.3
40
N.A.
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
66.6
80
80
N.A.
73.3
53.3
N.A.
46.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
20
0
0
10
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
0
50
10
0
10
10
50
20
0
0
0
0
% D
% Glu:
70
0
0
10
10
10
20
0
0
30
0
0
70
10
10
% E
% Phe:
0
0
0
0
10
0
0
20
0
0
0
40
0
0
0
% F
% Gly:
10
0
10
20
0
0
0
0
0
10
0
10
0
10
0
% G
% His:
0
0
0
0
0
10
0
0
20
0
0
0
0
0
0
% H
% Ile:
0
40
0
0
0
20
0
0
10
0
20
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
20
0
0
0
10
0
0
0
% L
% Met:
0
20
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
0
30
0
10
0
0
10
30
0
0
20
0
0
0
% N
% Pro:
0
0
10
10
10
40
0
20
10
0
0
0
0
60
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
30
10
10
70
20
10
0
50
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
10
0
0
0
10
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
10
20
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _