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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RXFP2
All Species:
18.79
Human Site:
S351
Identified Species:
45.93
UniProt:
Q8WXD0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXD0
NP_570718.1
754
86453
S351
L
H
K
N
Q
F
E
S
L
K
Q
L
Q
S
L
Chimpanzee
Pan troglodytes
XP_522654
754
86705
S351
L
H
K
N
Q
F
E
S
L
K
Q
L
Q
S
L
Rhesus Macaque
Macaca mulatta
XP_001118169
717
82892
S320
E
S
L
K
Q
L
Q
S
L
D
L
E
R
I
E
Dog
Lupus familis
XP_532702
763
87486
Y346
I
Q
A
D
Q
F
D
Y
L
V
K
L
K
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZZ5
737
82925
S334
V
H
K
N
Q
F
G
S
L
K
Q
L
Q
S
L
Rat
Rattus norvegicus
Q6R6I6
758
87164
Y341
I
E
V
N
Q
F
D
Y
L
A
K
L
K
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510674
996
112423
G583
V
Y
E
D
Q
F
D
G
L
K
Y
L
Q
S
L
Chicken
Gallus gallus
XP_420385
763
87614
F346
I
Q
I
D
Q
F
D
F
L
T
K
L
K
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695264
473
52835
T98
G
Y
L
Q
E
L
A
T
D
C
Q
V
E
Q
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733115
765
87196
E366
H
I
S
S
S
L
M
E
P
L
N
I
S
F
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
88.1
49.2
N.A.
80.5
52.9
N.A.
59.5
52.1
N.A.
35.6
N.A.
32.1
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
91.1
67.3
N.A.
87
71.5
N.A.
67.6
70.5
N.A.
44
N.A.
51.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
40
N.A.
86.6
46.6
N.A.
53.3
40
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
73.3
N.A.
93.3
73.3
N.A.
86.6
73.3
N.A.
40
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
30
0
0
40
0
10
10
0
0
0
0
0
% D
% Glu:
10
10
10
0
10
0
20
10
0
0
0
10
10
0
10
% E
% Phe:
0
0
0
0
0
70
0
10
0
0
0
0
0
10
0
% F
% Gly:
10
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% G
% His:
10
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
30
10
10
0
0
0
0
0
0
0
0
10
0
10
0
% I
% Lys:
0
0
30
10
0
0
0
0
0
40
30
0
30
0
0
% K
% Leu:
20
0
20
0
0
30
0
0
80
10
10
70
0
0
80
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
40
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
20
0
10
80
0
10
0
0
0
40
0
40
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
10
10
10
10
0
0
40
0
0
0
0
10
70
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% T
% Val:
20
0
10
0
0
0
0
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
0
0
0
20
0
0
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _