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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GEMIN6 All Species: 22.42
Human Site: S146 Identified Species: 54.81
UniProt: Q8WXD5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXD5 NP_079051.9 167 18824 S146 Y G P E N C S S S N E I I L S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110016 166 18662 S146 Y G P E N C S S S N E I I L S
Dog Lupus familis XP_532941 166 18670 S145 Y G P E N C S S P N E I I L S
Cat Felis silvestris
Mouse Mus musculus Q9CX53 166 18732 S145 Y A P E N C S S S N E I I L S
Rat Rattus norvegicus NP_001009466 166 18766 S145 Y A P E N C S S S N E F I L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521351 138 15092 L118 N S S N E I I L S R V Q G L I
Chicken Gallus gallus XP_423929 167 18815 S146 Y G P E E C S S S N E I I L S
Frog Xenopus laevis NP_001090473 104 12008 H84 E T K D R L A H L F T P R E T
Zebra Danio Brachydanio rerio XP_001336386 178 19762 Q148 G D C S C A N Q I I L A R V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121104 92 10509 T72 K E Q N D I L T I E N I L S I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.1 91.6 N.A. 85.6 82.6 N.A. 56.8 59.8 32.9 38.2 N.A. N.A. 24.5 N.A. N.A.
Protein Similarity: 100 N.A. 99.4 95.2 N.A. 94 91.6 N.A. 68.8 77.8 47.3 59.5 N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 86.6 N.A. 13.3 93.3 0 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 86.6 N.A. 13.3 93.3 20 13.3 N.A. N.A. 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 0 10 10 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 10 0 10 60 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 10 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 10 0 60 20 0 0 0 0 10 60 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % F
% Gly: 10 40 0 0 0 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 20 10 0 20 10 0 60 60 0 20 % I
% Lys: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 10 10 10 0 10 0 10 70 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 20 50 0 10 0 0 60 10 0 0 0 0 % N
% Pro: 0 0 60 0 0 0 0 0 10 0 0 10 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 10 0 0 0 10 0 0 10 % Q
% Arg: 0 0 0 0 10 0 0 0 0 10 0 0 20 0 0 % R
% Ser: 0 10 10 10 0 0 60 60 60 0 0 0 0 10 60 % S
% Thr: 0 10 0 0 0 0 0 10 0 0 10 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _