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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASKIN1 All Species: 14.24
Human Site: S1330 Identified Species: 28.48
UniProt: Q8WXD9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXD9 NP_065815.1 1431 149814 S1330 A S P A K P P S P G A P A L H
Chimpanzee Pan troglodytes XP_523265 1472 154891 R1407 G R C M G P A R A E A D G D A
Rhesus Macaque Macaca mulatta XP_001084114 1449 151732 S1351 T S P V K P P S P G A P A L H
Dog Lupus familis XP_853631 1347 141422 S1282 G L Q S G S A S P S P A P S P
Cat Felis silvestris
Mouse Mus musculus Q6P9K8 1431 150477 S1332 A S P V K P P S P G T P A L H
Rat Rattus norvegicus Q8VHK2 1430 150329 S1331 A S P A K P P S P G A P A L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507411 400 42074 H335 Q G L S K P S H A R A Q P R P
Chicken Gallus gallus XP_414857 1448 153132 P1357 S P A K P L S P G T Q P Q Q V
Frog Xenopus laevis Q6DD51 1205 130900 T1140 E A S S R E Q T C I P Q Q S I
Zebra Danio Brachydanio rerio XP_692620 1293 139986 Q1228 S A L T A E G Q N V L V H K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392417 814 88839 R749 P L S Q V Y K R R S R D M E T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795586 2231 243152 P1855 P A V S Q P P P P P A P P P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.6 95 85.5 N.A. 90.2 90.2 N.A. 20.3 72.1 38.2 43.4 N.A. N.A. 22.5 N.A. 26.6
Protein Similarity: 100 88.4 96.1 87.4 N.A. 93 93.1 N.A. 24.1 79.2 51.7 56.8 N.A. N.A. 35 N.A. 39.2
P-Site Identity: 100 13.3 86.6 13.3 N.A. 86.6 93.3 N.A. 20 6.6 0 0 N.A. N.A. 0 N.A. 33.3
P-Site Similarity: 100 13.3 86.6 20 N.A. 86.6 93.3 N.A. 26.6 13.3 26.6 13.3 N.A. N.A. 0 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 25 9 17 9 0 17 0 17 0 50 9 34 0 9 % A
% Cys: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 17 0 9 0 % D
% Glu: 9 0 0 0 0 17 0 0 0 9 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 9 0 0 17 0 9 0 9 34 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 25 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % I
% Lys: 0 0 0 9 42 0 9 0 0 0 0 0 0 9 0 % K
% Leu: 0 17 17 0 0 9 0 0 0 0 9 0 0 34 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 17 9 34 0 9 59 42 17 50 9 17 50 25 9 25 % P
% Gln: 9 0 9 9 9 0 9 9 0 0 9 17 17 9 9 % Q
% Arg: 0 9 0 0 9 0 0 17 9 9 9 0 0 9 9 % R
% Ser: 17 34 17 34 0 9 17 42 0 17 0 0 0 17 0 % S
% Thr: 9 0 0 9 0 0 0 9 0 9 9 0 0 0 9 % T
% Val: 0 0 9 17 9 0 0 0 0 9 0 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _